Hauv daim ntawv ntawm cov ntsiav tshuaj, Novostat tsis muaj nyob, qhov no yog daim ntawv uas tsis muaj nyob ntawm cov tshuaj. Nws yog tsim tawm tsuas yog nyob hauv daim ntawv ntawm tsiav tshuaj. Cov tshuaj muaj cov cim qhia txog kev mob siab, nws tau siv hauv cov tshuaj los ua kom cov roj (cholesterol) sib luag thiab ua rau tus neeg sawv cev tiv thaiv tsis txaus.
Cov ntawv tso tawm thiab muaj pes tsawg leeg
Cov tshuaj muaj nyob hauv tsiav tshuaj, cov tshuaj nquag hauv lawv yog atorvastatin calcium trihydrate.
Lub cev ntawm cov tshuaj ntsiav yog dawb thiab khoom, lub hau muaj lub teeb beige-daj xim. Lub ntsiab tivthaiv muaj nyob hauv tus nqi 10, 20, 40 lossis 80 mg. Ib qho kev sib xyaw ntxiv yog sawv cev los ntawm lactose monohydrate, sodium lauryl sulfate, cellulose, calcium carbonate, povidone thiab magnesium stearate. Cov tshuaj ntsiav nws tus kheej yog tsim los ntawm cov nkaws nrog qhov sib ntxiv ntawm titanium dioxide thiab zas E172.
Cov pob ntim cov khoom noj muaj 10 lub tshuaj thiab muab faib rau hauv lub thawv hauv qhov nyiaj ntawm 3 lub hlwv.
Cov pob ntim cov khoom noj muaj 10 lub tshuaj thiab muab faib rau hauv lub thawv hauv qhov nyiaj ntawm 3 lub hlwv. Capsules tuaj yeem muag hauv cov thawv yas ntawm 10, 20, 30, 40, 50, 60 lossis 100 pcs. Hauv plawv thawv ntawv tso rau 1 qhov zoo li no.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
INN ntawm cov tshuaj yog Atorvastatin.
ATX
Cov tshuaj muaj ATX code C10AA05.
Pharmacological kev txiav txim
Kev kho kom zoo ntawm Novostat tau muab vim yog cov nquag tivthaiv - atorvastatin. Cov compound no belongs rau statins thiab ua kom pom cov cuab yeej hypocholesterolemic. Nws inhibits kev ua haujlwm ntawm HMG-CoA reductase, ua yeeb yam xws li kev sib tw inhibitor nrog kev xaiv. Daim paib hais tshwj xeeb yog pib mevalonate txoj hauv kev ntawm biosynthesis ntawm steroids, ib qho yog cov roj (cholesterol).
Kev kho kom zoo ntawm Novostat tau muab vim yog cov nquag tivthaiv - atorvastatin.
Atorvastatin tseem ua rau muaj qhov nce ntxiv ntawm cov neeg tshwj xeeb hepatoreceptors, ua rau muaj kev sib cais ntau ntxiv ntawm cov lipoproteins tsawg ntom (LDL). Ua tsaug rau kev ua haujlwm ntawm cov tshuaj, cov concentration poob:
- tag nrho cov roj (cholesterol) - los ntawm 40% (ntawm qhov nruab nrab);
- apoB - los ntawm 51%;
- LDL - los ntawm 42%;
- triglycerides - los ntawm 24%.
Nyob rau tib lub sijhawm, qhov nce hauv high-density cholesterol-lipoproteins (HDL) thiab apoA tau sau tseg.
Cov tshuaj no tseem ua haujlwm zoo rau cov neeg mob uas muaj homozygous daim ntawv ntawm tsev neeg hypercholesterolemia, uas yog qhov tsis txaus ntseeg rau kev ua ntawm lwm cov lipid-txo cov tshuaj. Raws li qhov tshwm sim ntawm kev noj, txoj kev pheej hmoo ntawm kev tsim mob hlab ntsha hlwb, lwm yam kev mob plawv, ischemia nrog angina pectoris thiab mob plawv nres, mob plawv tuag tsawg. Tsis muaj cov teebmeem carcinogenic thiab mutagenic tau pom.
Cov Tshuaj Pharmacokinetics
Atorvastatin nrawm rau hauv lub plab zom mov, nce mus rau qhov ntshav siab tshaj plaws 1-2 teev tom qab kev tswj hwm, tab sis nws txoj kev nyab xeeb tsis tshaj 14% vim malabsorption thiab qhov tshwm sim "thawj-dhau". Txog 98% khi rau cov ntshav protein, yog li hemodialysis tsis muaj nuj nqis. Hauv cov khoom noj muaj, qhov feem uas thaum cov tshuaj mus rau hauv cov hlab ntshav khiav qeeb qeeb.
Nrog kev mob rau daim siab, cov concentration ntawm atorvastatin nce ntau.
Cov tshuaj metabolism hauv feem ntau tshwm sim hauv daim siab. Raws li cov chaw muag tshuaj cov haujlwm, qee yam ntawm nws cov tshuaj tiv thaiv tsis tau qis dua cov khoom qub - lawv suav txog kwv yees li 70% ntawm qhov cuam tshuam siv ntawm HMG-CoA reductase. Nrog rau cov zis, tsis pub ntau tshaj 2% ntawm cov koob tshuaj uas noj nws yog cais tawm.
Nrog kev mob rau daim siab, cov concentration ntawm atorvastatin nce ntau. Ib nrab-lub neej ntawm cov tshuaj yog 14 teev, tab sis cov tshuaj kho tau ntev txog 30 teev tom qab noj 1 koob tshuaj ntawm Novostat.
Kev ntsuas rau siv
Ua ke nrog kev kho kev noj haus thiab kev tawm dag zog, cov tshuaj tau raug sau kom tau txais txiaj ntsig hypolipidemic ntawm statins - txo cov roj cholesterol, LDL, tswj kev nce siab ntawm apolipoprotein B thiab triglyceride tebchaw. Kev taw qhia rau kev siv:
- hypercholesterolemia (thawj, tsev neeg lossis tsis-muaj keeb);
- hyperglyceridemia;
- hyperlipidemia ua ke:
- ua txhaum ntawm lipoprotein metabolism;
- dysproteinemia hom II (a thiab b);
- Fredrickson hom IV lipid pathology, qhia kev tawm tsam kev kho kev noj haus;
- dysbetalipoproteinemia thiab hais txog txawv txav.
Lwm lub cuab yeej yog kws kho rau kev tiv thaiv cov kab mob plawv, tsis hais txog cov roj (cholesterol) hauv lub cev:
- ntshav qab zib;
- cov neeg haus luam yeeb;
- cov neeg mob ntshav siab;
- cov neeg mob HDL tsawg;
- cov neeg muaj keeb caj ces rau cov kab mob ntawm cov hlab plawv.
Cov tshuaj yog tseem siv tau rau cov neeg mob hypercholesterolemia nrog kev tiv thaiv kab mob thib ob, mob plawv nres, mob caj dab, tawm tsam lub plawv tsis ua hauj lwm thiab txo kev ploj tuag. Tsis tas li, cov tshuaj yog tshuaj yog tsim nyog, nqa tawm kev ntsuas los ua kom rov qab lub vascular phab ntsa (rov qab kho).
Cov Yuav Tsum Muaj
Cov tshuaj yuav tsum tsis txhob noj nrog qhov tsis haum rau tshuaj atorvastatin, lactose tsis txaus lossis lwm yam tshuaj ntawm cov tshuaj. Lwm yam contraindications:
- daim siab mob
- nce kev ua si ntawm daim siab enzymes;
- cawv ntev ntev;
- mob hnyav kis hnyav;
- teeb meem metabolic;
- lub cev tsis muaj zog txaus;
- cev xeeb tub thiab pub niam mis;
- hnub nyoog txog 10 xyoo
Novostat raug txwv tsis pub muaj lub cev tsis muaj zog txaus.
Nrog saib xyuas
Qhov tshwj xeeb yuav tsum tau siv rau hauv qhov tsis muaj qhov tsis txaus electrolyte, endocrine cuam tshuam, keeb kwm ntawm kev mob ntshav siab. Nws tsis pom zoo kom xaiv Novostat rau menyuam yaus thiab tub ntxhais hluas.
Yuav noj li cas
Ua ntej koj yuav tsum sim ua kom cov roj (cholesterol) nyob rau lwm qhov, nrog rau kev saib xyuas cov kab mob tseem ceeb thiab poob phaus (nrog cov rog los yog ib txwm nyiam nws).
Cov tshuaj ntsiav tau qaug cawv tsis hais txog ntawm lub sijhawm lossis nruab hnub. Kev kho mob tsis ua tiav tam sim ntawd - tsawg kawg 2 lub lis piam yuav tsum tau dhau mus txij thaum pib noj Novostat. Thiab tsuas yog tom qab 4 lub lis piam cov nyhuv yuav ntau thiab yuav nyob twj ywm li ntawd mus txog rau thaum kawg ntawm kev kho mob hauv chav kawm. Tus kws kho mob sau ntawv muab ib qhov muab tshuaj thiab ntsuas tus neeg mob lub sijhawm. Cov koob tshuaj txhua hnub yog nyob ntawm seb qhov mob ntshav siab npaum li cas, cov hom phiaj kho thiab tus neeg tau txais kev pab los kho.
Plasma lipid concentration yog tshuaj xyuas tsis tu ncua thiab tshuaj kho tau kho. Rau kev tiv thaiv lub hom phiaj, cov tshuaj yog siv hauv qhov tsawg kawg nkaus.
Nrog ntshav qab zib
Statins ua rau muaj kev nce ntxiv hauv cov piam thaj hauv qab, uas yog qhov yooj yim los ntawm kev noj zaub mov zoo, kev tawm dag zog thiab cov tshuaj tiv thaiv kab mob ib txwm muaj. Koob tshuaj yuav tsis haum.
Cov tshuaj ntsiav tau qaug cawv tsis hais txog ntawm lub sijhawm lossis nruab hnub.
Sab sij huam
Ntau yam kev phiv tshuaj tuaj yeem tshwm sim.
Los ntawm cov kabmob hauv nruab nrog
Mloog tsis zoo.
Los ntawm cov leeg nqaij thiab pob txha sib txuas
Myopathy, mob myositis, mob caj dab, mob leeg.
Kev kho mob txoj hnyuv
Dyspepsia, kev poob siab tsis zoo, raws plab, pancreatitis.
Hematopoietic plab hnyuv siab raum
Tsawg cov platelet concentration.
Nruab nrab hauv lub paj hlwb
Cov migraines, insomnia, neuropathy, paresthesia, mob pob txha tsis muaj zog, kiv taub hau.
Los ntawm qhov zis, muaj qhov ua kom tsis muaj zog ntawm lub zog erection.
Los ntawm lub tshuab ua pa
Bronchospasm.
Los ntawm genitourinary system
Eakened erection, lub raum tsis ua haujlwm.
Los ntawm cov hlab plawv system
Rectal los ntshav.
Los ntawm ib sab ntawm cov metabolism
Hloov pauv nyob rau hauv cov ntshav qab zib.
Tsawg tsawg zaus, cov ntsiav tshuaj tuaj yeem ua rau do hau.
Kev ua xua
Urticaria, pob tsuas, anaphylaxis.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Koj yuav tsum caiv tawm ntawm cov haujlwm uas yuav tsum muaj lub siab xav paub.
Cov lus qhia tshwj xeeb
Tsis txhob siv rau qhov poob phaus - cov tshuaj tsis muaj cov khoom ntawd.
Siv rau lub sijhawm qub
Tsis tas yuav hloov cov koob tshuaj.
Dosage hloov hauv cov neeg laus tsis tsim nyog.
Txiag tej menyuam
Koj tsis tuaj yeem tshaj tawm cov tshuaj rau cov menyuam yaus hnub nyoog qis dua 10 xyoo. Nws siv rau hyperlipidemia yog tias tus me nyuam muaj kev pheej hmoo lossis muaj qhov tsis txaus siab rau lub plawv mob nrog lub siab ua rau lub siab tuag. Cov tshuaj yog siv nrog qis qis ntawm kev qhia noj haus. Sijhawm dhau los, koj yuav tsum yauv mus tawm dag zog rau kev tawm dag zog thiab kho tus kab mob. Txoj kev pheej hmoo ntawm kev tsim myopathy yog qhov siab.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj tsis tuaj yeem siv los ntawm cov poj niam cev xeeb tub thiab cov poj niam muaj hnub nyoog yug me nyuam, qhov muaj peev xwm ua kom cev xeeb tub yog qhov muaj txiaj ntsig vim kev tsis saib xyuas txog kev tiv thaiv. Cov leej niam uas tseem muaj menyuam hauv tsev laus kuj tsis sau tshuaj los kho kom txog thaum ua tiav kev pub mis niam.
Siv rau lub siab ua haujlwm tsis zoo
Cov kab mob hnyav ntawm lub siab ua haujlwm thiab nce kev ua haujlwm ntawm transaminases yog nruj contraindication noj Novostat.
Noj ntau dhau
Muaj kev cuam tshuam cuam tshuam ntawm daim siab thiab rhabdomyolysis. Nws raug nquahu kom yaug lub plab thiab noj lub siab. Txoj kev kho mob tsuas yog mob tus yam ntxwv.
Nyob rau hauv rooj plaub ntawm overdose, ib qho kev ua txhaum ntawm daim siab yog ua tau.
Kev cuam tshuam nrog lwm yam tshuaj
Kev siv tib lub Novostat nrog Erythromycin, Cyclosporin, Niacin, azoles thiab fibroic acid npaj muaj kev pheej hmoo ntawm myopathy. Cov koob tshuaj siab heev tuaj yeem ua rau dhia hauv qhov siab ntawm digoxin. Erythromycin, clarithromycin thiab kua txiv kab ntxwv qaub ntau ntxiv atorvastatin qib. Cov kev hloov pauv tau hauv cov chaw muag tshuaj muaj txiaj ntsig ntawm ethinyl estradiol thiab norethisterone tshuaj tiv thaiv. Thaum muaj cov tshuaj colestipol, qhov lipid-txo qis qis ntawm ob qho tshuaj yeeb tshuaj sib txuam ua ke.
Cawv tau zoo
Nws raug nquahu kom tsis txhob haus cawv.
Analogs
Cov tshuaj nquag ntawm Novostat yog ib feem ntawm cov tshuaj no:
- Atorvastatin;
- Atoris;
- Torvacard
- Tulip;
- Livostor;
- Atorvacor thiab lwm yam
Cov tshuaj nquag ntawm Novostat yog ib feem ntawm Tulip.
So haujlwm rau Novostat los ntawm lub tsev muag tshuaj
Nws tsis muaj tshuaj nyob hauv cov tsev luam.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Nws yog tso tawm tsuas yog thaum nthuav qhia ntawm daim ntawv qhia.
Nqi
Capsules 10 mg nqi los ntawm 60 rubles. rau 10 pcs.
Cia rau cov Novostat
Cov tshuaj yuav tsum khaws cia ntawm qhov kub txog + 25 ° C kom deb ntawm kev tshav ntuj.
Hnub tas sij hawm
3 xyoos
Chaw tsim tshuaj paus
Hauv Tebchaws Russia, Novostat yog tsim los ntawm ALSI Pharma CJSC thiab Biocom CJSC.
Kev txheeb xyuas txog Novostat
Polina, 24 xyoos, Lipetsk
Cov tshuaj raug txwv rau cov yawg vim muaj cov roj (cholesterol) siab. Nws haus cov tshuaj tau ntev, nws qhov mob zoo zuj zus. Tsuas yog nws tsim nyog los soj ntsuam txhua lub sijhawm kom tus yawg tsis ua txhaum kev noj haus. Peb txaus siab rau cov nyhuv ntawm cov tshuaj; tsis muaj kev tsis txaus siab txog cov kev mob tshwm sim.
Olga, 54 xyoos, Vyazemsky
Vim tias muaj cov roj (cholesterol) ntau, Kuv yuav tsum noj cov tsiav tshuaj no, thiab tseem niaj hnub mus tom tsev kho mob, feem ntau ua kev ntsuam xyuas thiab mus noj zaub mov. Tsis muaj qhov tshwm sim tsis zoo. Los sis tej zaum lawv tsis muaj zog, thiab kuv tsis tau mloog zoo. Kev nyab xeeb pib pib txhim kho qhov chaw hauv ib lim tiam. Tau haus tag nrho cov kev kawm, thawj zaug hauv lub sijhawm ntev kuv tuaj yeem hais tias kuv xav zoo.
