Cov txiaj ntsig ntawm thrombo ACC hauv ntshav qab zib

Cov tshuaj uas tswj cov ntshav viscosity tau muab faib ua ob hom: cov tshuaj tiv thaiv (cov leeg ntshav) thiab cov tshuaj tiv thaiv kab mob (tus neeg sawv cev uas tiv thaiv platelet adhesion). Thrombo ACC belongs rau cov pab pawg tom kawg thiab yog npaj rau kev kho mob ntawm cov neeg mob kev txom nyem los ntawm cov roj metabolism tsis txaus, mob ntshav qab zib mellitus lossis ntshav siab.

Lub npe thoob ntiaj teb

Acetylsalicylic acid. Hauv Latin - Acidum acetylsalicylicum.

Thrombo ACC yog npaj rau kev kho mob ntawm cov neeg mob kev txom nyem los ntawm cov roj metabolism tsis txaus, mob ntshav qab zib mellitus lossis ntshav siab.

ATX

B01AC06

Tso cov ntawv thiab cov nyob ua ke

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm puag ncig biconvex dawb ntsiav tshuaj coated nrog ib zaj duab xis txheej. Chav tsev ntawm cov tshuaj muaj 50 lossis 100 mg ntawm cov tshuaj nquag - acetylsalicylic acid. Raws li cov ntu muaj:

• mis nyuj qab zib;
• microcrystalline cellulose;
• colloidal silicon dioxide;
• cov hmoov txhuv nplej siab.

Cov txheej txheej enteric muaj xws li talc, ethyl acrylate copolymer, triacetin thiab methacrylic acid. Cov tshuaj ntsiav muaj rau hauv blister pob khoom ntawm 14 lossis 20 daim. Hauv ib daim ntawv qhia cardboard rau 14 units ntawm cov tshuaj muaj 2 lub hlwv, rau 20 ntsuas - 5 lub hlwv.

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm puag ncig biconvex ntsiav tshuaj ntawm cov xim dawb.

Pharmacological kev txiav txim

Acetylsalicylic acid (ASA) muaj cov cuab yeej tshuaj tiv thaiv kab mob uas tiv thaiv kev ua kom tsis haum rau cov ntshav ntshav. Lub chaw nquag muaj nyob hauv chav kawm ntawm cov tshuaj uas tsis muaj tshuaj steroidal (NSAIDs), yog ib qho tsim los ntawm salicylic acid. Kev kho mob ua kom zoo yog nyob ntawm qhov tsis paub tseeb kev tsis txaus ntseeg ntawm cyclooxygenase. Thaum cov enzyme yog tshuaj tiv thaiv, kev tsim tawm ntawm prostaglandins, thromboxane thiab prostacyclins cuam tshuam. Raws li kev tawm tsam kev zais cia ntawm thromboxane A2, platelet tsim, kev sib koom ua ke (clumping) thiab platelet sedimentation yog txo.

Cov nyhuv antiplatelet tseem ua rau lub lim tiam tom qab siv ib zaug. Xws li lub sijhawm ua haujlwm ntev ntawm acetylsalicylic acid yog siv rau kev kho mob thiab tiv thaiv ntawm ischemic, kab mob varicose, myocardial infarction.

Cov Tshuaj Pharmacokinetics

Thaum muab tshuaj ntawm qhov ncauj, acetylsalicylic acid nrawm nrawm 100% hauv cov hnyuv me. Cov ntsiav tshuaj tsis ua rau lub plab zom mov vim qhov muaj ntawm daim nyias nyias. Thaum lub sij hawm nqus, qhov kev kho me ntsis ib feem rau salicylic acid tshwm sim. Qhov tshuaj lom neeg no hloov pauv hauv daim siab ua daim ntawv ua salicylates.

Thaum nws nkag rau hauv cov ntshav, ASA khi rau 66-98% nrog cov plasma protein thiab tau faib ceev rau cov nqaij mos. Ntshav kis tsis tshwm sim. Qhov kev tshem tawm ib nrab-lub neej mus txog 15-20 feeb. Kev tso zis mob tsuas yog 1% ntawm txoj kev lees txais tshuaj nyob hauv nws thawj daim ntawv. Tus so tawm hauv lub cev hauv daim ntawv ntawm metabolites. Nrog rau kev ua haujlwm li qub ntawm nephrons, 80-100% ntawm cov tshuaj tau txaws los ntawm ob lub raum rau 1-3 hnub.

Thaum muab tshuaj ntawm qhov ncauj, acetylsalicylic acid nrawm nrawm 100% hauv cov hnyuv me.

Kev ntsuas rau siv

Cov tshuaj yog npaj los tiv thaiv mob plawv ntawm lub plawv mob thaum tus neeg mob muaj kev pheej hmoo (mob ntshav siab, rog dhau, muaj hnub nyoog laus dua 50 xyoo, ua tsis zoo, mob ntshav qab zib mellitus). Hauv kev kho plawv, cov kws kho mob tshwj xeeb muaj cai sau tshuaj rau hauv cov teeb meem hauv qab no:

• raws li kev ntsuas ntawm kev tiv thaiv ntawm thromboembolism tom qab kev tiv thaiv tsis zoo thiab kev phais mob ntawm cov hlab ntsha: mob hlab ntshav o hla kev sib tsoo, stenting, angioplasty;
• nrog txoj hlab ntshav sib sib zog nqus;
• rau kev kho mob rau mob kub taub hau vim mob khaub thuas;
• tiv thaiv kev mob ntshav hauv lub hlwb;
• rau kev kho mob ntawm hom mob angina ruaj khov thiab tsis khov;
• los tiv thaiv kev txhim kho ntawm kev rov ua lub plawv nres;
• raws li kev tiv thaiv mob stroke, suav nrog cov xwm txheej nrog cerebrovascular kev sib tsoo.

Cov tshuaj yog siv los tiv thaiv pulmonary embolism tom qab lub sijhawm ntev vascular fixation, uas tau ua nyob rau hauv lub sijhawm tom qab cev tas.

Thrombo ACC yog qhov kev tiv thaiv kev tiv thaiv rau thromboembolism.

Cov tshuaj yog tshuaj rau cov hlab ntsha sib sib zog nqus thrombosis.

Qee zaum cov Thrombo ACC yuav pab kom zoo mob thaum kub taub hau vim mob khaub thuas.

Cov tshuaj Thrombo ACC yog tshuaj tiv thaiv kev hloov ncig hauv lub hlwb.

Rau kev kho mob kom ruaj khov thiab tsis ruaj khov angina pectoris, Trombo ACC yog kho.

Thrombotic ACC siv rau kev tiv thaiv kom rov muaj dua lub plawv nres.

Raws li kev tiv thaiv kab mob stroke, nws yog txoj kev coj los sau Thrombo ACC.

Cov Yuav Tsum Muaj

Ib qho tshuaj tsis pom zoo lossis raug txwv rau kev siv rau hauv cov xwm txheej nram no:

• nce kev cuam tshuam ntawm cov ntaub so ntswg mus rau acetylsalicylic acid thiab lwm yam NSAIDs;
• hnyuv ntshav;
• lactase intolerance, malabsorption ntawm monosaccharides;
• ulcerative erosive lesions ntawm lub plab zom mov;
• hemorrhagic diathesis;
• ua ke nrog tshuaj methotrexate ntau npaum ntawm 15 mg nrog rau kev siv tib lub lis piam;
• mob raum lossis daim siab tsis txaus;

Cov cuab yeej tsis pom zoo siv rau cov neeg mob lub siab tsis ua si III thiab IV chav kawm.

Nrog saib xyuas

Ceev faj yog yuav tsum tau nyob rau hauv lub sij hawm ntawm kev kho tshuaj rau cov neeg mob uas muaj cov kab mob, kab mob thiab kab mob:

• bronchial hawb pob;
• mob gout
• mob rau sab hauv lub plab thiab duodenum;
• kab mob ua pa ntev;
• lub raum creatinine tshem tawm tsawg dua 30 ml / min;
• II lub sijhawm cev xeeb tub;
• daim siab ua haujlwm siab;
• txoj hlab pas reflux esophagitis;
• quav nyab kub;
• ua ke siv cov tshuaj pleev xim, tiv thaiv mob, los tiv thaiv rheumatic.

Nws raug nquahu kom sab laj nrog koj tus kws kho mob txog kev tshem tawm txoj kev kho tshuaj ua ntej npaj kev phais mob.

Nrog lub plab zom mov, thrombo ACC yuav tsum tau ua nrog ceev faj.

Thrombotic ACC yog noj nrog ceev faj nyob rau hauv bronchial hawb pob.

Rau cov kab mob ntawm cov txheej txheem ntawm daim paib ntev ntev, cov tshuaj yuav tsum tau ua nrog ceev faj.

Reflux txoj hlab nqos mov ntawm txoj hlab pas - qhov taw qhia nyob rau hauv uas thrombo ACC yuav tsum tau ua nrog ceev faj.

Kev ceev faj yuav tsum tau siv rau hauv kev siv tshuaj ua ke siv tshuaj kho mob, tiv thaiv mob, tiv thaiv mob rheumatic thiab Thrombo ACC.

Yuav noj li cas

Cov ntsiav tshuaj yog npaj rau cov thawj coj hauv qhov ncauj. Kev kho mob nyhuv yog manifested tsuas yog thaum kho mob ntev. Qhov ntau thiab ntau npaum li cas ntawm kev kho mob yog txiav txim los ntawm tus kws kho mob tshwj xeeb, uas tso siab rau tus yam ntxwv ntawm tus neeg mob (hnub nyoog, hnyav lub cev), kev kuaj ntshav thiab kuaj lub cev. Qib qhov mob hnyav thiab hom mob cuam tshuam rau kev kho mob kiag.

Thaum sawv ntxov lossis yav tsaus ntuj

Thaum teem cov tshuaj ib zaug siv ib hnub, nws pom zoo kom noj cov tshuaj thaum hmo ntuj ua ntej mus pw. Thaum siv 2 lossis ntau dua cov ntsiav tshuaj, nws yog ib qho tsim nyog yuav tau soj ntsuam lub sijhawm nruab nrab ntawm cov koob tshuaj 12 teev. Hauv qhov no, ib tus neeg haus tshuaj thaum sawv ntxov thiab yav tsaus ntuj.

Ua ntej lossis tom qab noj mov

Nws raug nquahu kom noj cov tshuaj ua ntej noj mov kom thiaj li tiv thaiv kom tsis txhob mob plab hnyuv los ntawm txoj hnyuv kom mob ntxiv. Hauv qhov no, nws yuav tsum haus cov ntsiav tshuaj nrog qhov muaj kua ntau.

Noj cov tshuaj rau ntshav qab zib

Cov roj (cholesterol) yog tso rau hauv daim ntawv ntawm cov rog plaques ntawm cov phab ntsa vascular. Yog li, cov kab mob ntshav qab zib yog qhov txaus ntshai - rau cov neeg uas nquag muaj tshwm sim ntawm cov kab mob plawv (rog dhau, haus luam yeeb, muaj hnub nyoog laus, tawg). Muaj ntshav qab zib, 100 mg ib hnub twg yog cov ntawv kho mob.

Muaj ntshav qab zib, 100 mg ib hnub twg yog cov ntawv kho mob.

Yuav siv sijhawm ntev npaum li cas

Cov neeg mob uas muaj mob tsis txaus ntawm lub plawv cov ntshav tau qhia kom coj tus neeg sawv cev antiplatelet mus tas lub neej. Cov tshuaj yuav pab txo cov ntshav txhaws hauv chav hauv lub plawv. Cov pab pawg neeg no suav nrog tib neeg kev mob plawv los ntawm kev mob plawv, atrial fibrillation, angina pectoris, lub plawv tsis ua haujlwm.

Cov neeg mob uas muaj ntau cov ntshav muaj ntshav ntau, khov kho cov ntshav txhaws, noj cov tshuaj nyob rau hauv 1-2 lub lis piam kom txog thaum cov plasmaets ceev ploj tag.

Sab sij huam

Yog tias muaj qhov tsis zoo tshwm sim, sab laj nrog koj tus kws kho mob uas yuav hloov cov tshuaj lossis kho qhov tshuaj txhua hnub.

Kev kho mob txoj hnyuv

Los ntawm lub plab zom mov, qhov tshwm sim ntawm xeev siab thiab ntuav. Muaj qee zaus, noj tshuaj pab ua rau lub qhov txhab ntawm lub plab thiab duodenum, nrog los ntshav. Kev tsis sib haum xeeb hauv daim siab vim muaj kev nce siab ntawm aminotransferases nyob rau hauv hepatocytes tau sau tseg.

Noj Thrombo ACC yuav ua rau txo qis ntawm qhov pom tseeb.

Lopirel tuaj yeem ua rau mob taub hau.

Kiv taub hau yog phiv cov tshuaj Lopirel.

Thaum noj Thrombo ACC, cov pos hniav los ntshav yuav tshwm sim.

Cov hlab ntsha hauv lub hlwb yog ib qho kev phiv los ntawm cov tshuaj.

Thaum kho mob Lopirel, xeev siab thiab ntuav tej zaum yuav tshwm sim.

Hematopoietic plab hnyuv siab raum

Cov qauv hauv qab no yog cai:

• mob ntshav roj;
• los ntshav ntxiv hauv cov zis;
• cov pos hniav los ntshav;
• hemolytic anemia;
• epistaxis, tom qab los ntshav.

Kev zais hemorrhage yog nrog cyanosis thiab asthenia.

Nruab nrab hauv lub paj hlwb

Kev puas siab puas ntsws los ntawm cov kab mob hauv lub paj hlwb (tinnitus, kiv taub hau, mob taub hau, tsis pom kev thiab hnov ​​lus) tuaj yeem yog tus tsos mob tshaj plaws.

Kev ua xua

Nrog rau kev nkag siab ntau ntxiv rau cov tshuaj ntawm cov tshuaj, tawm pob, khaus khaus, erythema, Quincke's edema, anaphylactic ceeb, rhinitis, bronchospasm, o ntawm lub qhov ntswg ntawm qhov ntswg thiab pharynx tuaj yeem tsim kho.

Rau kev ua xua rau kev ua xua, pab neeg tu mob yuav tsum raug hu.

Cov lus qhia tshwj xeeb

Cov tshuaj nquag hauv cov koob tshuaj qis tuaj yeem ua rau qhov pib lossis qhov ua rau lub zog ntawm gout nyob rau ntawm qhov muaj qhov xav tau tsim nyog, thaum nyob rau qhov siab kawg qhov teeb meem hypoglycemic yuav tshwm sim. Cov cuab yeej kawg yuav tsum yog nyob rau hauv lub siab los ntawm cov neeg mob kev mob ntshav qab zib.

Cov tshuaj nquag hauv cov koob tshuaj qis tuaj yeem ua rau qhov pib lossis ua kom tsis zoo ntawm gout.

Acetylsalicylates muaj cov txiaj ntsig ntev ntev uas yuav kav rau 6-7 hnub tom qab kev tswj hwm, uas ua rau muaj kev pheej hmoo los ntshav thaum phais mob. Txog kev tiv thaiv, cov tshuaj raug muab tso tseg ib lis piam ua ntej kev phais mob.

Cawv tau zoo

Cov tshuaj Ethanol uas muaj hauv cawv tsub kom ntau ntxiv ntawm kev ua kom lub plab zom mov ua rau lub plab zom mov.

Cuam tshuam rau lub peev xwm los tswj cov tshuab

Nyob rau lub sijhawm kho cov tshuaj no, nws raug nquahu kom tsis txhob tsav tsheb, sib cuam tshuam nrog cov txheej txheem tsis yooj yim, thiab los ntawm lwm cov haujlwm uas yuav tsum muaj kev kub siab thiab cuam tshuam sai.

Siv thaum cev xeeb tub thiab lactation

Lub cuab yeej ywj pheej nkag mus rau qhov kev tiv thaiv placental, uas yog vim li cas nyob rau thawj peb lub hlis ntawm kev txhim kho embryonic nws tuaj yeem cuam tshuam kev tso ntawm lub ntsiab ntawm cov plab hnyuv siab raum thiab cov tshuab. Thaum yug los, tus menyuam yuav muaj lub siab tsis zoo lossis lub ntsej muag tawg.

Hauv lub sijhawm thib III, cov tshuaj pib qeeb tus txheej txheem yug me nyuam thiab muaj peev xwm ua rau txoj leeg khov ntawm qhov faus hauv lub embryo. Yog li, tus neeg sawv cev tiv thaiv kab mob tsuas yog siv rau thaum muaj xwm txheej ceev thaum muaj kev phom sij rau leej niam lub neej ntau dua qhov kev pheej hmoo ntawm cov kab mob pathologies hauv tus menyuam.

Hauv nruab nrab lub hlis luv, kev siv cov tshuaj nrog qhov tshuaj tsis ntau dua 150 mg rau ib hnub yog tso cai. Nrog rau kev kho mob ntev, nws raug nquahu kom tshem tawm kev pub mis niam.

Hauv cov neeg mob laus dua li 50 xyoo, muaj kev pheej hmoo ntawm kev noj ntau tshaj.

Teem caij thrombo ACC rau cov menyuam yaus

Hauv thaum yau, nws yog txwv tsis pub siv mus txog 18 xyoo. Qhov tshwj xeeb yog rickets thiab Kawasaki syndrome.

Siv rau lub sijhawm qub

Hauv cov neeg mob laus dua li 50 xyoo, muaj kev pheej hmoo ntawm kev noj ntau tshaj.

Noj ntau dhau

Nrog kev tsim txom cov tshuaj, nws muaj peev xwm los tsim lub chaw soj ntsuam cov duab ntawm kev noj ntau dhau zoo ib yam li cov tsos mob ntawm intoxication hnyav:

• mob taub hau thiab kiv taub hau;
• lub suab nrov hauv pob ntseg;
• tsis meej pem thiab tsis nco qab;
• nce hws;
• nce ua pa vim muaj hyperventilation, pulmonary edema;
• arrhythmia, hypotension, mob plawv dhia;
• ua txhaum ntawm cov dej-ntsev rau cov metabolism;
• lub plab zom mov;
• kev nkees nkees, hnov ​​qab;
• coma, mob leeg.

Thaum muaj mob ntau dhau, yuav tsum tau pw hauv tsev kho mob sai nrog lub plab zom mov thiab adsorbent yog qhov tsim nyog. Kev kho yog ua kom tswj tau lub luag haujlwm tseem ceeb thiab txhawb nqa acid-puag, dej-electrolyte tshuav nyiaj li cas. Nrog qhov normalization ntawm tus mob, kev kho mob yam ntxwv kev ua haujlwm.

Yog tias dhau ntawm kev siv tshuaj ntau dhau, yuav tsum tau pw hauv tsev kho mob sai nrog lub plab zom mov yog qhov tsim nyog.

Kev cuam tshuam nrog lwm yam tshuaj

Nrog rau kev siv acetylsalicylic acid tib lub sij hawm nrog lwm cov tshuaj, cov kev coj ua hauv qab no yog ua tau:

1. Txo cov ntshav plasma concentration ntawm methotrexate vim tias kev txav chaw ntawm lub tom kawg los ntawm cov nqaijrog.
2. Qhov ntxim nyiam ntawm kev los ntshav nce ntxiv, synergism (nce kho cov nyhuv ntawm ob qho tshuaj) yog pom thaum ua ke nrog cov tshuaj anticoagulants, clopidogrel, tus neeg sawv cev thrombolytic.
3. Kev noj ntau dhau yuav tshwm sim thaum kho nrog Digoxin.
4. Kev mob toxicity ntawm valproic acid yog txhim kho vim nws txoj kev tsiv tawm ntawm cov protein.
5. Ibuprofen ua rau tsis muaj zog kho cov tshuaj, vim tias nws yog nws qhov chaw muag tshuaj.

Ua ke nrog glucocorticosteroids, ib qho kev nce ntawm excretion ntawm salicylates thiab lub zog ntawm cov nyhuv ntawm antiplatelet tau sau tseg.

Analogs

Yog tias nws tsim nyog yuav tsum txiav tawm cov tshuaj, tus kws kho mob muaj cai tshaj tawm lwm txoj kev kho tshuaj nrog rau ib qho hloov chaw, xws li:

• Cardiomagnyl;
• Txwv tsis pub muaj
• Aspenorm;
• Thrombogard;
• Godasal;
• Detralex

Cardiomagnyl suav hais tias yog ib qho tshuaj noj los ntawm cov tshuaj Thrombo ACC.

Qee zaum tshuaj Aspenorm qee lub sijhawm siv hloov Trombo ACC.

Qee zaum Thrombogard tau sau tseg kom tsis siv tshuaj Thrombo ACC.

Qee zaum, hloov Trombo ACC, Detralex yog tshuaj.

Tshuaj aspirin Cardio, uas tau nqus hauv lub cev tas nrho, raug xa mus rau cov duab analogues hauv cov nquag sib txuas.

Tshuaj aspirin Cardio, uas tau nqus hauv lub cev tas nrho, raug xa mus rau cov duab analogues hauv cov nquag sib txuas.

Cov ntsiab lus ntawm lub tsev muag tshuaj tawm

Cov tshuaj raug muag hauv cov tsev muag tshuaj yam tsis muaj tshuaj.

Nqe rau Thrombo ACC

Tus nqi nruab nrab ntawm cov tshuaj txawv ntawm 37 txog 160 rubles, nyob ntawm ntau cov ntsiav tshuaj hauv cov thawv ntawv thawv.

Cia rau cov mob ntawm cov tshuaj Thrombo ACC

Nws yog qhov yuav tsum tau khaws lub pob ntim hauv qhov chaw qhuav, txwv los ntawm lub teeb rau ntawm qhov kub txog +25 ° C. Tsis txhob cia cov yeeb tshuaj poob rau hauv menyuam yaus txhais tes.

Hnub tas sij hawm

3 xyoos

Kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog Thrombo ACC

Evgeny Filippov, kws kho plawv, Rostov-on-Don

Kuv sau ntawv rau TromboAss tsuas yog tom qab soj ntsuam nruj ntawm tus neeg mob uas tsis muaj peev xwm tiv thaiv kev ua haujlwm. Qhov ua tau zoo ntawm cov tshuaj tau muaj pov thawj nws tus kheej hauv cov txheej txheem kev kuaj mob. Hauv kuv qhov kev coj ua, kuv pom qhov kev txhim kho rau txoj kev nyob zoo ntawm cov neeg mob tom qab 1-2 lub lis piam ntawm kev kho. Kuv tsis xav qhia tshuaj rau koj tus kheej.

Valery Krasnov, 56 xyoo, Ryazan

Kuv tau noj TromboAss tau 5 xyoos, vim tias tus kws kho mob tau sau tseg vim hais tias ntawm kab mob vascular. Ua ntej yuav noj cov ntsiav tshuaj, phais ntshav khov tau ua tiav ntau zaug. Tom qab ua ntshav cov ntshav, cov mob zoo dua thiab tsis muaj kev cuam tshuam ntxiv. Ua raws li cov lus qhia rau kev siv, tsis pom muaj qhov tsis zoo.

Maria Utkova, 34 xyoo, Yekaterinburg

Hauv kev sib txuas nrog thrombosis ntawm hemorrhoids thaum cev xeeb tub, ThromboAss tau raug tshuaj tom qab kev phais mob kom tshem tawm cov ntshav txhaws. Tsis muaj qhov exacerbation ntawm hemorrhoids, nrog rau kev tshwm sim ntawm thrombosis. Txawm tias lub mus ob peb vas tau txhim kho. Tsuas pub pub mis rau menyuam noj xwb. Cov kws kho mob tau hais tias cov tshuaj no tau muab zais cia hauv cov qog plab thiab yuav ua rau lub cev loj hlob.