Lisinopril 20 - ib qho tshuaj kho kom zoo rau cov tsos mob ntawm kev mob ntshav siab.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lisinopril.
Lisinopril 20 - ib qho tshuaj kho kom zoo rau cov tsos mob ntawm kev mob ntshav siab.
ATX
Qhov ATX code yog C09AA03.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob hauv daim ntawv foos. Cov ntsiav tshuaj muaj cov lisinopril nyob rau hauv daim ntawv ntawm lub cev qhuav dej. Cov ntsiab lus ntawm cov tshuaj nquag yuav sib txawv. Ib ntsiav tshuaj muaj 5 mg, 10 mg lossis 20 mg ntawm lisinopril.
Pharmacological kev txiav txim
Cov tshuaj nquag siv ntawm tus neeg sawv cev zwm rau pawg ntawm angiotensin-hloov enzyme inhibitors. Raws li tshuaj ntawm cov yeeb yaj kiab, cov ntsiab lus ntawm angiotensin 2 thiab aldosterone hauv cov roj ntsha poob qis.
Ntshav siab kuj txo qis vim yog ntau yam ua kom zais zis ntawm bradykinin, yam khoom uas muaj cov nyhuv vasodilating. Vasodilation ua rau qhov txo qis ntawm cov hlab ntshav leeg tsis kam. Qhov kev thauj mus los ntawm lub siab nqaij pob txha yog txo qis, uas tuaj yeem tso tawm cov ntshav cov ntshav nrog cov pob txha tsawg. Cov kev siv cov ntshav ntws hauv cov hlab ntsha ntxiv tseem nce me ntsis.
Thaum noj ntawm qhov ncauj, theem ntawm cov ntshav siab poob qis tom qab 1 teev. Qhov kev ua tau zoo tshaj plaws tau tiav hauv 6 teev.
Thaum noj ntawm qhov ncauj, theem ntawm cov ntshav siab poob qis tom qab 1 teev. Qhov kev ua tau zoo tshaj plaws tau tiav hauv 6 teev. Lub sijhawm ntsuas ntawm lub peev nyiaj npaum li cas ntawm cov tshuaj yeeb dej caw. Thaum siv nyob rau hauv cov koob tshuaj txheem, kev ua haujlwm yuav kav ib hnub.
Lisinopril muaj cov tshuaj tiv thaiv hypotensive ruaj khov thoob plaws hauv tag nrho lub sijhawm siv. Kev tsis ua haujlwm sai sai ntawm txoj kev kho tsis ua rau txo qis ntshav siab.
Dua li ntawm qhov tseeb tias lisinopril cuam tshuam kev ua haujlwm ntawm angiotensin-hloov pauv enzyme, cuam tshuam cov metabolism hauv cov kab mob angiotensin-aldosterone, nrog rau kev siv ntev, cov tshuaj kuj txo qis hauv cov neeg mob uas muaj qis renin.
Ntxiv nrog rau qhov kev ua kom zoo hauv siab, qhov tshuaj kuj tseem txo qis cov tshuaj albumin tawm hauv cov zis. Lisinopril tsis cuam tshuam rau cov ntshav cov ntshav qabzib.
Cov Tshuaj Pharmacokinetics
Kev rho tawm ntawm cov nquag ua haujlwm ntawm tus neeg sawv cev tshwm sim los ntawm mucosa ntawm txoj hnyuv me. Lub bioavailability ntawm cov tshuaj yog nyob ntawm tus yam ntxwv ntawm tus neeg mob lub cev. Nws nyob ntawm 5 txog 50%.
Qhov siab tshaj plaws zoo hauv cov ntshav thaum noj ntawm qhov ncauj yog pom tom qab 7 teev. Suction tsis nyob ntawm lub sijhawm noj mov.
Qhov siab tshaj plaws zoo hauv cov ntshav thaum noj ntawm qhov ncauj yog pom tom qab 7 teev.
Cov tshuaj muaj zog tsis khi rau ntshav thauj peptides. Kev pom tshwm sim tsuas yog mob nrog cov angiotensin hloov ua enzyme. Lisinopril tuaj yeem dhau los ntawm BBB hauv qhov ntau thiab tsawg.
Cov khoom siv tsis ua haujlwm tsis yauv hloov pauv hauv metabolic. Kev tshem tawm yuav siv sij hawm nyob rau hauv nws thawj daim foos. Cov zis yog dhau los. Ib nrab-lub neej yog 12 teev.
Kev tsim kho lub raum tsis zoo yog 50 ml / min. Ib feem ntawm cov tshuaj tau nthuav tawm sai sai, ib feem txuam nrog ACE tseem nyob hauv cov hlab ntsha mus ntev.
Kev ntsuas rau siv
Lisinopril yog tshuaj rau kev kho mob ntawm cov kab mob hauv qab no:
- qhov tseem ceeb arterial tawg;
- lub plawv tsis ua hauj lwm;
- AMI rau hauv cov neeg mob nrog cov hemodynamic ruaj khov;
- nephropathy mob los ntawm teeb meem metabolic nyob rau hauv cov ntshav qab zib tsis yog insulin-tiv thaiv ntshav qab zib, ntshav siab.
Cov tshuaj yog tshuaj rau lub plawv tsis ua hauj lwm.
Thaum dab tsi siab
Kev Kho Mob nrog angiotensin-hloov ua enzyme inhibitors, uas suav nrog lisinopril, yog qhia rau txhua tus neeg mob ntshav siab. Lawv raug kho ob qho tib si nrog kev mob sib luag hauv cov ntshav siab, thiab nrog rau kev hnyav thiab mob hnyav tawg.
Thawj cov qib ntawm kub siab yog suav tias yog kev pheej hmoo tawm hauv systolic siab mus rau 140-159 hli Hg. thiab diastolic siab txog 90-99 hli Hg
Tau pom qhov nce ntshav nce siab rau cov lej saum toj no, tsis txhob noj tshuaj tus kheej. ACE inhibitors yuav tsum yog tus kws kho mob sau tseg.
Cov Yuav Tsum Muaj
Lisinopril tsis tau raug teeb meem nyob rau hauv cov teeb meem hauv qab no:
- tus neeg mob tau muaj kev sib xyaw nrog tus kheej rau cov tshuaj nquag lossis lwm yam khoom sib xyaw ua ke sib xyaw ua ke;
- mob hlwb;
- ob leeg lub raum leeg txoj hlab ntsha;
- myocardial infarction;
- tsis muaj txhij txhua ntawm bcc;
- cardiogenic poob siab;
- cov neeg mob tom qab hloov raum;
- lub raum tsis ua haujlwm;
- nqaim ntawm aortic lumen;
- plawv hypertrophy;
- mitral valve stenosis;
- hyperaldosteronism.
Nws yog contraindicated yuav siv cov tshuaj rau myocardial infarction.
Yuav ua li cas noj Lisinopril 20
Cov twj siv yog siv 1 zaug nyob rau ib hnub. Kev noj tshuaj tsis yog nyob ntawm lub sijhawm noj mov. Cov ntsiav tshuaj noj thaum sawv ntxov.
Qhov ntau npaum li cas thiab kev siv sijhawm ntev li cas ntawm kev kho mob yog xaiv los ntawm tus kws kho mob, coj mus rau hauv tus account tus yam ntxwv ntawm txhua tus neeg mob. Lub xeev ntawm lub raum, cov tshuaj noj tau coj mus, thiab qhov ntsuas nce siab ntawm cov ntshav siab yog suav nrog.
Kev muab tshuaj rau txhua hnub yog 2.5 mg. Qhov nce yog ua tau tom qab 2-4 lub lis piam, thaum cov nyhuv ntawm kev kho mob pom. Cov koob tshuaj yuav nce ntxiv kom txog thaum cov tshuaj yuav pab tswj tau cov ntshav siab. Qhov siab tshaj plaws pom zoo rau kev noj tshuaj txhua hnub yog 40 mg.
Hauv lub plawv tsis ua hauj lwm, kev kho mob pib nrog tib yam tsawg kawg ib hnub ib zaug, uas tom qab ntawd tuaj yeem mus txog qib 20 mg.
Hauv qhov mob myocardial infarction, 5 mg ntawm lisinopril yog cov tshuaj. Tom qab, qhov koob tshuaj nce mus rau tus txheej txheem 10 mg. Kev kho mob kav rau 6 lub lis piam. Yog hais tias tus neeg mob systolic cov ntshav siab qis dua 120 hli Hg, kev noj tshuaj yog txo tsawg dua 2 zaug.
Qhov ntau npaum li cas thiab kev siv sijhawm ntev li cas ntawm kev kho mob yog xaiv los ntawm tus kws kho mob, coj mus rau hauv tus account tus yam ntxwv ntawm txhua tus neeg mob.
Nrog ntshav qab zib
Kev teem caij ntawm qhov tsawg kawg txhua hnub hauv kev noj tshuaj yog pom zoo. Qhov nce yog tau ua tiav los ntawm kev saib xyuas ntawm tus kws kho mob.
Cov neeg mob uas muaj ntshav qab zib hom 2 thiab nephropathy ntawm thawj theem tau txais 10 mg ntawm cov tshuaj. Qhov tshuaj ntau ntau txhua hnub yog 20 mg.
Sab sij huam
Feem ntau, cov tshuaj tau yooj yim zam. Cov tsos mob tshwm sim feem ntau: hypotension, lub plawv dhia, tsis nco qab, orthostatic vau. Ua xua tshwm sim zoo li ua anaphylaxis los yog ntsej muag o tuaj yeem tshwm sim.
Kev kho mob txoj hnyuv
Thaum kho, cov tsos mob tsis txaus siab hauv qab no tuaj yeem tshwm sim:
- qhov ncauj qhuav
- hloov cov quav;
- tsam plab;
- anorexia;
- tsis pom kev cuam tshuam hepatic;
- kab mob siab;
- pancreatitis
- xeev siab
- ntuav
- mob plab.
Hematopoietic plab hnyuv siab raum
Cov kab ke hauv qab no tshwm sim tau:
- thrombocytopenia;
- qhov txo qis hauv cov qe ntshav dawb;
- anemia
- pancytopenia;
- pathology ntawm cov qog ntshav;
- eosinophilia.
Nruab nrab hauv lub paj hlwb
Tej zaum yuav teb rau kev kho nrog qhov pom ntawm cov tsos mob hauv qab no:
- pw tsaug zog;
- kev chim siab;
- tsaug zog
- depressive kev ntshawv siab;
- tsis meej pem txog txoj kev nco qab;
- tinnitus;
- peripheral neuropathy;
- cramps
- ob lub zeem muag
- tshee hnyo
- paresthesia;
- hnov kev sib koom tes.
Los ntawm lub tshuab ua pa
Cov tsos mob hauv qab no tej zaum yuav tshwm sim:
- kev hnoos
- o ntawm cov hlab ntsws;
- hawb pob
- mob hlab ntsws
- rhinitis;
- hemoptysis;
- spasm ntawm cov leeg huv ntawm bronchi;
- ua pa nyuaj.
Ntawm ib sab ntawm daim tawv nqaij
Cov tawv nqaij tuaj yeem teb rau kev kho nrog nrog kev pom ntawm:
- hyperhidrosis;
- rhiab rhiab rau UV rays;
- ua pob;
- psoriasis-zoo li hloov;
- stratification ntawm cov ntsia hlau phaj;
- alopecia;
- pemphigus;
- erythema;
- dermatitis.
Los ntawm genitourinary system
Tej zaum yuav tshwm sim:
- oliguria;
- anusia
- o ntawm lub raum cov ntaub so ntswg;
- proteinuria;
- Neeg Raug Ntse;
- tsawg tsav sib deev;
- gynecomastia.
Endocrine system
Cov tsos mob ntawm tus mob ntshav qab zib yog ua tau.
Cov tsos mob ntawm tus mob ntshav qab zib yog ua tau.
Cov lus qhia tshwj xeeb
ACE cov tshuaj tiv thaiv kab mob tuaj yeem ua rau hyperkalemia thiab ua kom cov ntsev txo qis hauv cov hlab ntshav. Qhov no yuav tsum tau saib xyuas cov qib hluav taws xob tsis tu ncua thaum kho.
Siv rau lub sijhawm qub
Qhov siab tshaj plaws zoo ntawm cov tshuaj hauv cov ntshav ntshav hauv cov neeg laus dua li qhov ntsuas pom hauv cov neeg mob hluas los ntawm 1.5-2 zaug. Qhov no yuav yog qhov laj thawj ntawm kev kho qhov tseeb ntawm kev noj tshuaj txhua hnub ntawm cov tshuaj.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Kev ceev faj yuav tsum tau siv thaum siv cov tshuaj no, txij li nws tuaj yeem ua rau pom kev tshwm sim ntawm pathological los ntawm cov leeg hlwb. Muaj kev ua txhaum ntawm kev sib koom ua ke ntawm kev txav chaw thiab kev saib xyuas ntawm txoj kev mloog, uas tuaj yeem ua rau muaj teeb meem hauv kev tsav tsheb thiab cov txheej txheem nyuaj.
Muaj kev ua txhaum ntawm kev sib koom ua ke ntawm kev txav chaw thiab kev saib xyuas ntawm qhov saib xyuas, uas tuaj yeem ua rau txoj kev nyuaj ntawm kev tsav tsheb.
Siv thaum cev xeeb tub thiab lactation
Kev kho nrog lisinopril yog contraindicated thaum cev xeeb tub. Tsis pom zoo teem sij hawm tshuaj rau txoj kev kho mob rau cov pojniam muaj menyuam tsis taus.
Kev muab tshuaj Lisinopril rau 20 tus menyuam
Cov kev tshawb fawb tau tshawb fawb txog kev siv tshuaj rau kev kho mob siab ntsws hauv menyuam yaus 6-18 xyoo. Qib qhov kev nqus ntawm cov neeg mob no yog li 30%. Qhov siab tshaj plaws kev xav zoo nyob rau hauv lub raum thiab daim siab ua haujlwm tsis txawv qhov ntawd hauv cov laus.
Thaum tsis muaj contraindications, lisinopril tuaj yeem kho rau cov menyuam yaus.
Noj ntau dhau
Kev siv ntau dhau ntawm cov tshuaj tuaj yeem ua rau vau, poob siab, ua kom lub cev tsis haum ntawm electrolyte tshuav, tsis nco qab, thiab mob raum tsis ua haujlwm.
Yog tias xav tias noj ntau dhau lawm, nws yog qhov yuav tsum tau yaug tus neeg mob lub plab, sau ntawv rau tus neeg ua khawv koob. Yog tias tus neeg mob muaj cov tsos mob loj, yuav tsum tau pw hauv tsev kho mob. Hauv tsev kho mob, koj yuav tsum saib xyuas lub plawv thiab lub ntsws ntsig kev ua haujlwm, rov qab lub bcc, li qub roj electrolyte tshuav.
Kev noj tshuaj ntau dhau yuav ua rau tsis nco qab.
Kev cuam tshuam nrog lwm yam tshuaj
Kev siv tshuaj sib xyaw nrog lisinopril yog contraindicated nrog:
- Aliskiren - vim qhov kev pheej hmoo ntawm kev tuag.
- Estramustine - nce qhov kev pheej hmoo ntawm kev phiv tshuaj los ntawm lub cev tiv thaiv kab mob.
- Baclofen - potentiates cov nyhuv ntawm lisinopril, uas tuaj yeem ua rau txo cov ntshav siab dua.
- Sympathomimetics - txo qis kev ua haujlwm ntawm kev kho mob.
- Tricyclic cov tshuaj tiv thaiv kev ntxhov siab.
- Cov tshuaj tiv thaiv.
- Tshuaj rau tshuaj loog.
Nrog saib xyuas
Kev sib xyaw ntawm lisinopril nrog cov tshuaj potassium-sparing diuretics tuaj yeem ua rau nce ntxiv hauv qib ntawm cov keeb kwm no hauv cov hlab ntshav. Xws li kev sib xyaw ua ke yuav tsum saib xyuas cov qib hluav taws xob tsis tu ncua.
Cov tshuaj potentiates hypoglycemic cov nyhuv ntawm cov tshuaj noj rau ntshav qab zib. Kev txo cov ntshav qab zib yuav xav tau ntau npaum li tau kho.
Haus dej cawv tsis pom zoo rau cov neeg mob ntshav siab.
Cawv tau zoo
Haus dej cawv tsis pom zoo rau cov neeg mob ntshav siab. Ua ke nrog ACE inhibitors yuav nce qhov tshwm sim ntawm kev mob tshwm sim.
Kev sib xyaw nrog cov tshuaj uas tsis yog tshuaj steroidal txo cov kev ua tau zoo ntawm kev kho. Kuj tseem yuav muaj kev tsis zoo hauv lub raum ua haujlwm mus txog rau kev txhim kho ntawm qhov tsis txaus ntseeg ntawm cov kabmob no.
Analogs
Cov analogues ntawm cov tshuaj no yog:
- Aurolyza;
- Vitopril;
- Dapril;
- Diroton;
- Zonixem;
- Irumed;
- Lysigamma;
- Lisighexal;
- Pob Ntse;
- Solipril.
Hnub so uas muaj nyiaj ntawm Lisinopril 20 los ntawm cov chaw muag tshuaj
Nws raug tso tawm raws li kws kho mob tau sau tseg.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tsis yog.
Nqi
Nyob ntawm qhov chaw ntawm yuav khoom.
Cia rau cov neeg mob rau cov tshuaj
Yuav tsum muab cia rau qhov kub thiab txias tsis tshaj + 25 ° C.
Hnub tas sij hawm
Tsis pub dhau 3 xyoos txij li hnub pib.
Cov tshuaj muaj nyob ntawm cov tshuaj.
Chaw tsim tshuaj paus Lisinopril 20
Nws yog tsim los ntawm lub tuam txhab Ratiopharm.
Kev txheeb xyuas txog Lisinopril 20
Cov kws kho mob
Maxim Pugachev, kws kho plawv, Moscow
Lisinopril yog ib qho kev kho mob zoo rau kev tawg. Kuv muab nws rau kuv cov neeg mob ob leeg ua kev kho mob monotherapy, thiab hauv kev sib xyaw nrog lwm tus neeg sawv cev. Rau cov neeg mob uas muaj mob hnyav ua mob, Kuv xav kho kev kho mob nrog diuretics ua ke nrog lisinopril. Nrog kev saib xyuas kom zoo los ntawm tus kws kho mob, xws li kev siv tshuaj kho tsis yog tsuas yog ua tau zoo, tab sis kuj tseem muaj kev nyab xeeb. Nws yog txhua yam hais txog qhov raug xaiv qhov ntau ntawm cov tshuaj.
Feem ntau kuv siv cov lisinopril + hydrochlorothiazide 12.5 mg regimen. Nws tsuas yog tsim nyog nco ntsoov tias lub diuretic tshem tawm sodium, uas tej zaum yuav xav tau saib xyuas nws cov ntsiab lus hauv cov ntshav. Qhov no yog ua los ntawm kev tswj hwm cov ntsev rau hauv cov zaub mov.
Alla Galkina, kws kho plawv, Moscow
Ib cov tshuaj uas paub zoo rau txhua tus kws kho mob. ACE inhibitors yog tshuaj rau txhua tus neeg uas tseem ceeb ntshav siab, vim tias lawv pab tswj ntshav siab. Nov yog txoj kev tawm xwb, vim nws yeej tseem kho tsis tau tus kab mob no kiag.
Noj Lisinopril nws yooj yim. Tsuas yog ib ntsiav tshuaj ib hnub twg yuav pab tswj kom ntshav siab. Koj tsuas yog yuav tsum xaiv cov tshuaj yog. Qee zaum nws yuav tsum tau muab tshuaj ntxiv, tab sis tsuas yog mob hnyav.
Nws yog txwv tsis pub coj kev txais tos ib txhij nrog Aliskiren, raws li muaj kev pheej hmoo tuag.
Cov neeg mob
Pavel, 67 xyoo, Ufa
Kuv tau mob mob plawv ntev ntev thiab kho ntshav siab tau ntau dua ib xyoos. Kuv tau sim tshuaj ntau, tab sis kuv tsis pom muaj ib qho zoo dua li Lisinopril. Pheej yig tshuaj uas pab tswj tau cov ntshav siab. Tsis txhob tos yuav cov tshuaj no, cov yeeb yaj kiab txawv teb chaws tsis muaj qhov zoo dua. Nov yog muab cov nyiaj yooj yooj yim.
Zhanna, 54 xyoo, Irkutsk
Kuv mob taub hau mob ntshav thib 2. Nws pib pom cov tsos mob 3 xyoos dhau los, thaum mob taub hau, kiv taub hau, tsis muaj zog, mob caj dab. Kuv tau mus cuag kws kho mob uas kuaj pom thiab kho kho mob. Txij thaum ntawd los kuv tau noj Lisinopril. Lub cuab yeej daws tau nrog nws txoj haujlwm, Kuv tsis paub txog kev phiv. Kuv xa tag nrho cov kev kuaj mob hauv lub sijhawm thiab mus ntsib kws kho mob rau kev sib tham. Thaum cov tshuaj yog txaus siab kiag li.
Gennady, 59 xyoo, Samara
Kuv noj Lisinopril txog li 3 lub hlis. Lub chav kawm ntawm txoj kev kho mob tau pib tam sim ntawd tom qab tus kws kho mob tau kuaj mob ntshav dhau los. Thaum kho, 2 zaug yuav tsum tau nce qhov ntau ntxiv ntawm cov tshuaj. Tam sim no noj 10 mg ib hnub twg. Kuv tau ua raws li no ntau npaum li 2 lub lis piam tam sim no. Lub siab rov qab mus rau qub. Kuv vam tias cov tshuaj yuav pab tswj nws hauv kev txwv ib txwm muaj thiab yav tom ntej.
