Atorvastatin lossis Simvastatin tau sau cia kom txo qis cov roj cholesterol thiab txhim kho cov kev zom zaub mov. Ob qho tshuaj tau siv ntev hauv kev kho mob, yog li ntawd, lawv tau pov thawj lawv tus kheej rau kev kho thiab kev tiv thaiv kab mob plawv.
Cov Cim Atorvastatin
Atorvastatin hais txog tshuaj lipid-txo qis los ntawm pab pawg ntawm statins. Atorvastatin calcium trihydrate (10.84 mg) yog ib yam khoom muaj sia uas cuam tshuam nrog kev tsim cov roj (cholesterol). Cov cuab yeej no pab txo qis cov lipoproteins tsawg (LDL) thiab qhov siab ntom ntom (HDL), thiaj li tiv thaiv kom tsis txhob muaj cov plahaum mob ntshav qab zib.
Atorvastatin lossis Simvastatin tau sau cia kom txo qis cov roj cholesterol thiab txhim kho cov kev zom zaub mov.
Tom qab noj, cov ntsiav tshuaj nkag mus rau hauv txoj hnyuv me, qhov chaw nws nkag mus rau hauv cov kab ke thoob plaws lub cev los ntawm nws cov phab ntsa. Lub bioavailability ntawm lub active tivthaiv yog 60%. Cov Hepatic enzymes ua qee cov txheej txheem ntawm cov tshuaj, thiab cov seem yog txaws tawm hauv lub cev nrog quav, tso zis thiab tawm hws.
Txhawb cov roj (cholesterol) hauv atherosclerosis, lub plaques hauv qhov loj thiab me capillaries yog qhov qhia tau tseem ceeb rau kev siv Atorvastatin. Nws kuj tseem pom zoo kom tau sau tshuaj rau kev tiv thaiv kab mob li no:
- ntshav qab zib hom 2;
- plawv nres;
- tus cwj nrag;
- ntshav siab
- angina pectoris;
- ischemia ntawm lub plawv.
Atorvastatin hais txog tshuaj lipid-txo qis los ntawm pab pawg ntawm statins.
Atorvastatin muaj lub peev xwm los ua kom lub cev ntau ntxiv nrog kev siv lub sijhawm ntev thiab qee cov kab mob pathologies, piv txwv li, yog tias lub siab lossis lub raum tsis ua haujlwm. Hauv qhov no, qhov ua kom tsis zoo ntawm cov tshuaj muaj cai. Tus neeg mob yuav yws yws ntawm kub taub hau, mob taub hau, ua kom tsis muaj zog, thiab ua haujlwm sai. Yog tias koj tsis quav ntsej tag nrho cov phiajcim no, ces qhov tshwm sim ntawm kev lom neeg lub cev ntau dua.
Cov yam ntxwv ntawm simvastatin
Cov tshuaj Simvastatin kuj yog nyob rau hauv pab pawg ntawm statins. Cov tshuaj tiv thaiv tsis haum tshuaj yog simvastatin. Muaj cov tsis suav nrog:
- titanium dioxide;
- lactose;
- povidone;
- citric acid;
- ascorbic acid;
- magnesium stearate, thiab lwm yam.
Simvastatin muaj qib siab ntawm kev nqus. Qhov siab tshaj plaws ntawm cov tshuaj nquag hauv cov ntshav tau tiav 1-1.5 teev tom qab kev tswj hwm. Tom qab 12 teev, cov qib no txo los ntawm 90%. Qhov tseem ceeb ntawm kev nthuav tawm yog los ntawm txoj hnyuv, hla raum, 10-15% ntawm cov nquag ua haujlwm yog tawm.
Lub hom phiaj tseem ceeb ntawm cov tshuaj yog txhawm rau txo cov roj hauv cov hlab plawv tsis xis nyob. Cov tshuaj yog kws kho nyob rau hauv cov xwm txheej zoo li no:
- kev pheej hmoo siab ntawm kev tsim mob atherosclerosis;
- thawj hypercholesterolemia (hom II a thiab II b);
- hypercholesterolemia thiab hypertriglyceridemia;
- rau kev tiv thaiv ntawm myocardial infarction, mob stroke, ischemic nres, atherosclerosis ntawm lub plawv hlab.
Lub hom phiaj tseem ceeb ntawm kev siv Simvastatin yog kom txo cov roj cholesterol hauv cov hlab plawv tsis zoo.
Sib piv ntawm Atorvastatin thiab Simvastatin
Sau tshuaj noj thiab xaiv tshuaj ntau npaum li cas yuav tsum yog tus kws paub tshwj xeeb uas coj mus rau hauv tus account tsis yog tsuas yog tus kab mob xwb, tab sis kuj yog qee tus yam ntxwv ntawm lub cev.
Qhov zoo sib xws
Ob leeg tshuaj yog nquag siv hauv kev kho plawv rau kev kho mob thiab tiv thaiv cov kab mob plawv thiab leeg.
Ob Atorvastatin thiab Simvastatin yog cov tshuaj zoo thiab muaj ib lub hom phiaj - txo cov roj hauv cov ntshav.
Lawv tseem tau sib sau ua ke los ntawm cov haujlwm hauv qab no:
- Cov tshuaj muaj cov tshuaj sib txawv, tab sis lactose nyob hauv ob qho tib si. Yog li, lawv yuav tsum tau ua kom zoo zoo nrog kev nkag siab zoo rau cov ntu ntu no.
- Ib qho kev mob tshwm sim hauv daim ntawv ntawm kiv taub hau yog yam ntxwv ntawm ob lub tshuaj. Vim li no, lub sijhawm kho, koj yuav tsum tsis kam tsav lub tsheb thiab ua haujlwm nrog cov txheej txheem npliag.
- Cov tshuaj yog contraindicated nrog rau lipid-txo cov tshuaj, vim hais tias myopathy yuav loj hlob tuaj. Yog tias, tawm tsam keeb kwm ntawm kev kho mob nrog Atorvastatin lossis Simvastatin, qhov kub tau nce thiab mob nqaij tau tshwm sim, tom qab ntawd cov tshuaj yuav tsum tau tso tseg, hloov lawv nrog analogues.
- Cev xeeb tub thiab lactation yog lwm qhov kev tiv thaiv. Cov poj niam thaum lub sijhawm kho yuav tsum siv tshuaj tiv thaiv.
- Nrog lub caij nyoog siv thiab noj ntau dhau, qhov ntxim siab ntawm cov kev mob tshwm sim yog qhov siab. Hauv cov xwm txheej zoo li no, ob lub raum thiab mob siab raug mob feem ntau. Yog li, nws raug txwv tsis pub tshaj qhov muab tshuaj los ntawm tus kws kho mob.
Dab tsi yog qhov txawv
Lub ntsiab sib txawv yog tias cov lus sib xyaw ntawm cov kev npaj tsis yog tib yam khoom ua muaj zog. Yog li, atorvastatin hais txog hluavtaws statins, uas muaj cov nyhuv ua kom ntev dua. Simvastatin yog lub ntuj statin nrog cov nyhuv luv luv.
Cov tshuaj qaug tshuaj ntawm Atorvastatin muaj zog dua, yog li, cov tshuaj no muaj ntau dua contraindications. Cov no suav nrog:
- cev xeeb tub thiab lactation;
- hnub nyoog txog 10 xyoo;
- cawv ntev ntev;
- nce tus nqi ntawm transaminases hauv cov ntshav;
- kev tsis haum tshuaj rau lactose;
- cov kab mob sib kis hauv cov theem mob ceev.
Simvastatin tsis pom zoo siv rau hauv cov teeb meem hauv qab no:
- ua kom lub cev tsis haum rau cov tshuaj;
- daim siab mob
- hnub nyoog me;
- cev xeeb tub thiab lactation;
- pob txha leeg mob.
Atorvastatin yog qhov tsis xav kom siv ib txhij nrog cov tshuaj tua kab mob thiab tshuaj tua kab mob. Simvastatin kuj tseem tsis tuaj yeem ua ke nrog HIV protease inhibitors thiab tshuaj anticoagulants. Tsis txhob noj txiv kab ntxwv qaub lossis haus cov txiv kab ntxwv kua txiv thaum kho nrog ntsiav tshuaj. Qhov kev sib xyaw ua ke no muaj peev xwm dhau qhov kev coj ua ntawm cov tshuaj nquag hauv cov ntshav.
Cov kev mob tshwm sim hauv qab no yuav tshwm sim thaum noj Simvastatin:
- teeb meem kev zom;
- insomnia
- mob taub hau
- ua txhaum ntawm saj thiab pom kev (tsis tshua muaj);
- nce ESR, kev txo qis hauv cov platelets thiab cov ntshav liab.
Thaum kho nrog Atorvastatin, cov neeg mob tuaj yeem ntsib tinnitus, nco teeb meem, thiab zoo nkaus li nkees tas li.
Tawm tsam tom qab ntawm kev noj Simvastatin, mob taub hau yuav tshwm sim.
Hemodialysis yog qhia nyob rau hauv kis mob ntawm kev noj ntau dhau ntawm simvastatin. Cov txheej txheem zoo li no yuav tsis zoo rau qhov xwm txheej zoo sib xws nrog Atorvastatin.
Uas yog pheej yig dua
Tus nqi ntawm cov tshuaj yog nyob ntawm lub teb chaws ntawm kev tsim khoom thiab ntau npaum li cas.
Simvastatin tsim nyob rau ntau lub tebchaws, suav nrog Russia, Fabkis, Serbia, Hungary, thiab Czech koom pheej. Tus nqi ntawm ib pob ntawm 30 ntsiav tshuaj ntawm 20 mg yuav yog 50-100 rubles. Tus nqi rau kev ntim tshuaj (20 pcs. Rau 20 mg) tsim hauv Czech koom pheej yog li 230-270 rubles.
Atorvastatin ntawm Lavxias ntau lawm tuaj yeem muas hauv khw muag tshuaj ntawm tus nqi no:
- 110 rub - 30 pcs. 10 mg txhua;
- 190 rub - 30 pcs. 20 mg txhua;
- 610 RUB - 90 pcs. 20 mg txhua.
Qhov twg yog qhov zoo dua - atorvastatin lossis simvastatin
Tsuas yog tus kws kho mob uas tuaj koom thiaj paub txog qhov tshuaj twg zoo dua tom qab tshuaj xyuas tus neeg mob, tab sis muaj qee yam tseem ceeb ntawm cov tshuaj:
- Cov nyhuv nrawm nrawm tuaj yeem ua tiav nrog Atorvastatin, li nws muaj cov tshuaj nquag nrog cov nyhuv zoo dua.
- Simvastatin ua rau muaj kev phiv tshuaj tsawg dua, uas yog qhov zoo ntawm cov tshuaj no. Thaum siv raug, tshuaj lom cov khoom siv ua paug tsis nthuav tawm hauv lub cev.
- Raws li kev soj ntsuam kev soj ntsuam ntawm cov tshuaj, nws tau ua pov thawj tias Simvastatin txo cov roj cholesterol ua teeb meem 25%, thiab Atorvastatin - los ntawm 50%.
Yog li, rau kev kho mob ntev ntev ntawm pathologies, Atorvastatin yuav tsum nyiam, thiab rau kev tiv thaiv cov mob vascular, nws yog qhov zoo dua los siv Simvastatin.
Kev Ntsuam Xyuas Rau Neeg Mob
Olga, 37 xyoo, Veliky Novgorod
Tom qab lub plawv nres, txiv tau xaj kom Simvastatin kom txo qis cov cholesterol. Cov kev kho mob kav ntev 4 lub hlis thiab lub sijhawm no tsis muaj kev phiv tshuaj. Qhov tsis pom tseeb ntxiv ntawm cov tshuaj yog tus nqi, rho tawm - tsawg ua haujlwm. Rov ua tas tas tsom pom hais tias qib uas cov roj (cholesterol) phem tsawg heev me ntsis. Txiv chim siab, vim tias nws muaj kev cia siab siab rau ib qho tshuaj. Kuv ntseeg tias simvastatin pab rau hauv qee qhov mob me me, thiab tsis nyob hauv kev nyuaj. Tam sim no peb tau kho nrog lwm txoj kev kho mob.
Maria Vasilievna, 57 xyoo, Murmansk
Thaum kuaj xyuas tom ntej, tus kws kho mob tau hais tias cov roj (cholesterol) tau nce siab me ntsis thiab pom zoo kom noj cov tshuaj statins. Kuv tau noj Simvastatin, ua raws kev noj haus thiab yoog raws li kev ua lub cev tsis tseem ceeb. Tom qab 2 lub hlis kuv dhau qhov kev txheeb xyuas zaum ob, uas txhua tus ntsuas tau rov qab zoo li qub. Kuv tsis tu siab tias kuv haus cov tshuaj, txawm hais tias ntau tus ceeb toom ntawm nws qhov kev tsis zoo thiab kev tsis muaj tseeb nyob hauv kuv cov ntshav. Kuv zoo siab tias qhov tshwm sim tau ua tiav. Kuv pom zoo nws!
Galina, hnub nyoog 50 xyoo, Moscow
Kuv ntshai thaum kuv hnov tus kws kho mob hais tias muaj ntau dua 8 cov roj (cholesterol). Kuv xav tias qhov kev kho mob yuav ntev thiab nyuaj. Atorvastatin raug sam tseg. Kuv tsis tau tso ib qho kev cia siab rau ntawm cov tshuaj, tab sis hauv vain. Tom qab 2 lub hlis ntawm kev kho mob, roj cholesterol mus rau 6. Kuv tsis cia siab tias cov tshuaj yuav pab tau. Kuv xav nco ntsoov tias kuv haus cawv nruj heev raws li kev pom zoo los ntawm tus kws kho mob thiab tsis muaj kev phiv tshuaj.
Ob leeg tshuaj yog nquag siv hauv kev kho plawv rau kev kho mob thiab tiv thaiv cov kab mob plawv thiab leeg.
Cov kws kho mob tshuaj xyuas txog Atorvastatin thiab Simvastatin
Egor Alexandrovich, hnub nyoog 44 xyoo, Moscow
Kuv tsis tshua muaj tshuaj Simvastatin, vim tias Kuv xav tias nws yog cov tshuaj ntawm lub xyoo pua xeem. Tam sim no muaj cov qauv tshiab niaj hnub no uas ua haujlwm ntau dua thiab muaj kev nyab xeeb dua. Piv txwv li, atorvastatin. Cov tshuaj no tsis tsuas yog muaj peev xwm txo qis cov roj (cholesterol) phem xwb, tab sis kuj txo qis kev pheej hmoo ntawm lub plawv thiab mob ntshav hlab ntsha. Daim foos tso tawm yooj yim.
Lyubov Alekseevna, 50 xyoo, Khabarovsk
Hauv kev xyaum kho mob, Kuv sim sau tshuaj Atorvastatin rau cov neeg mob yog tias tsis muaj contraindications. Kuv ntseeg tias cov tshuaj no ua tau ntau dua maj mam, tsis muaj kev cuam tshuam ntawm kev ua haujlwm ntawm cov khoom nruab nrog sab hauv thiab lub cev. Cov neeg mob tsis tshua yws txog cov kev mob tshwm sim, uas yog qhov tseem ceeb. Tom qab tag nrho, feem ntau cov nyiaj laus tuaj nrog qhov teeb meem zoo sib xws, uas twb muaj tus kab mob ntev lawm.
