Maninil yog cov tshuaj ntsiav tshuaj siv los kho mob ntshav qab zib hom 2. Cov tshuaj yeeb tshuaj yog glibenclamide. Muaj nyob hauv hwj ntawm 120 ntsiav tshuaj rau kev tswj hwm qhov ncauj. 5 mg glibenclamide nyob hauv ib lub tshuaj.
Qhov tshwm sim ntawm kev siv
Manin txo cov ntshav qabzib hauv cov ntshav, belongs rau chav kawm ntawm sulfonylurea derivatives.
Maninil rau cov ntshav qab zib:
- Txo postprandial (tom qab noj mov) hyperglycemia.
- Nws tsis muaj kev cuam tshuam tseem ceeb rau kev nce nrawm ntawm cov piam thaj.
- Ua kom muaj kev sib txuas ntawm b-hlwb ntawm tus txiav ntawm nws tus kheej insulin.
- Lowers tus txheeb ze insulin tsis txaus.
- Tsub kom qhov chaw tsis haum rau cov kws tshwj xeeb thiab cov ntaub so ntswg sib kis mus rau insulin.
- Nws tsis tshua muaj kev cuam tshuam cov insulin tsis kam.
- Txhawb kev rhuav tshem ntawm glycogen thiab cov synthesis ntawm qabzib hauv lub siab.
- Nws muaj cov nyhuv ua haujlwm antiarrhythmic, txo cov tsim ntawm cov ntshav txhaws.
- Nws txo txoj kev pheej hmoo ntawm kev tsim cov kev mob ntshav qab zib hauv qab no: mob ntsws (mob ntsws); hlab plawv (mob plawv); nephropathy (mob raum); retinopathy (pathology ntawm tus kab mob retina).
Cov nyhuv tom qab noj mannyl mob tsawv ntev dua 12 teev.
Kev kho mob ntshav qab zib yuav tsum muaj txhij txhua thiab suav nrog kev kho mob tsis zoo rau tshuaj, tab sis kuj noj zaub mov
Cov Khoom Qhia
Maninil raug pom zoo rau kev teem sijhawm ntawm hom 2 mob ntshav qab zib mellitus (daim ntawv tsis-insulin-tiv thaiv) nrog kev tsis txaus siab los ntawm cov kev kho mob tsis siv tshuaj (kev noj haus, mob ib ce lub cev).
Cov Yuav Tsum Muaj
Cov tshuaj tsis yog siv rau cov ntshav qab zib hom 1 (insulin-based daim ntawv), txo qis ntshav qabzib cov ntshav qis dua tus lej qub, qhov pom tshwm sim ntawm acetone derivatives nyob rau hauv cov zis, ntshav, lossis nrog kev txhim kho mob ntshav qab zib tsis xeev. Maninil yuav tsum tsis txhob noj thaum lub sijhawm cev tes taw thiab lactation. Nws tseem muaj qhov cuam tshuam hauv cov neeg mob uas decompensated cov kab mob ntawm daim siab thiab lub raum, nrog rau ib tus neeg tsis quav yeeb rau cov tshuaj.
Tsuas tshuaj thiab tswj hwm
Qhov ntau npaum ntawm cov tshuaj thiab lub sijhawm ntawm kev kho yog los ntawm tus endocrinologist raws li qib kev them nyiaj rau tus kabmob. Raws li txoj cai, ntsiav tshuaj tau noj 2 zaug hauv ib hnub, ib nrab teev ua ntej noj mov. Thaum lub sij hawm kho, qhov ntau npaum ntawm cov tshuaj hloov kho kom txog thaum lub txiaj ntsig kho yam xav tau. Qhov tsawg kawg ntawm kev kho mob ntawm cov tshuaj yog 0.5 ntsiav tshuaj, qhov siab tshaj plaws tau tso cai rau txhua hnub yog 3-4 ntsiav tshuaj.
Maninil muaj txoj kev noj tshuaj yooj yim, uas tso cai rau koj xaiv ib txoj kev kho mob rau txhua tus neeg mob
Sab sij huam
Cov kev mob tshwm sim hauv qab no yuav tshwm sim thaum kho maninil:
- ntshav tshuaj qis;
- hnyav;
- daim tawv nqaij ua pob;
- khaus
- lub plab zom mov;
- mob tej pob txha
- ntshav muaj pes tsawg leeg cuam tshuam;
- hyponatremia (txo qis hauv sodium hauv cov ntshav);
- hepatotoxicity;
- cov tsos ntawm cov protein nyob hauv cov zis.
Nrog rau qhov loj ntawm cov kev mob tshwm sim, cov tshuaj yog muab tso tseg thiab lwm txoj kev kho yog kho.
Cov lus qhia tshwj xeeb
Siv nrog ceev faj thaum noj clonidine, b-blockers, guanethidine, reserpine vim yog qhov nyuaj ntawm kev tshawb pom cov tsos mob ntawm tus mob qog ntshav qab zib. Thaum lub sijhawm kho mannil, noj zaub mov thiab saib xyuas ntshav qab zib yog qhov tsim nyog.
Maninil xav tau khaws cia rau hauv qhov chaw tsaus.
Feem ntau, cov tshuaj tau ua haujlwm tau zoo ob qho tib si hauv monotherapy ntawm hom 2 mob ntshav qab zib mellitus, thiab ua ke nrog lwm cov tshuaj uas muaj suab thaj.
