Oktolipen yog tshuaj kawg rau txoj kev daws teeb meem rau Txoj kev lis ntshav. Oktolipen nyob rau hauv hom ntshav qab zib hom 2 yog siv los tswj cov metabolism thiab cov lipid metabolism, txo cov ntshav qab zib thiab poob phaus ntxiv.
Cov tshuaj yog tseem siv dav rau lwm yam ntshav qab zib ua ib feem ntawm kev kho mob nyuaj. Oktolipen feem ntau muaj kev tshuaj xyuas zoo los ntawm cov neeg mob ntshav qab zib.
Oktolipen tseem muaj nyob hauv tshuaj ntsiav thiab daim foos.
Oktolipen
Oktolipen yog ib qho tshuaj tiv thaiv kab mob tsis zoo uas khi dawb. Cov txheej txheem no tshwm sim thaum lub sijhawm oxidative decarboxylation ntawm alpha-keto acids.
Raws li coenzyme, cov tshuaj txuam nrog hauv decarboxylation ntawm pyruvic acid thiab alpha-keto acids. Nws muaj peev xwm ua kom cov ntshav qabzib tsawg dua, nrog rau kev nce glycogen hauv daim siab thiab kov yeej cov tshuaj insulin. Yog li, nws tuaj yeem siv rau mob ntshav qab zib hom 2.
Thioctic acid yog ze rau B vitamins. Cov tshuaj no muaj cov teebmeem hauv qab no:
Akes Ua nrog kev tswj hwm kev ua haujlwm ntawm lipid thiab carbohydrate,
Txhim kho cov roj metabolism hauv lub cev,
Ua rau lub siab.
Cov tshuaj muaj:
1. tshuaj zoo siab,
2. tshuaj tua kab mob hlwb,
3. lipid-txo qis,
4. cov nyhuv hypoglycemic.
Nrog kev pab ntawm lub cuab yeej trophism ntawm neurons tau zoo tuaj, nrog rau txoj kev ua axonal thiab qhov hnyav ntawm haus dej cawv thiab mob ntshav qab zib polyneuropathy tsawg dua.
Cov tshuaj Okolipen tsuas yog kho los ntawm tus kws kho mob nkaus xwb. Nws raug txwv tsis pub koom nrog kev kho tus kheej nrog cov tshuaj no.
Octolipene hauv ampoules yog cov cuab yeej siv zog uas tsim nyog los tsim cov tshuaj pleev dej. Cov kua yog pob tshab, nrum hauv ntsuab thiab daj.
Hauv 1 milliliter ntawm cov tshuaj yog thioctic lossis lipic acid 30 mg. Ib qho ampoule muaj peb puas mg ntawm qhov khoom ntawd.
Ntu Cheebtsam yog:
- disodium edetate,
- ethylenediamine
- distilled dej.
Cov tshuaj muaj nyob rau hauv tsaus iav ampoules hauv ib qhov nyiaj ntawm 10 millilitres. Cov pob yog pob ntawv cardboard, hauv 1 ntim - 5 ampoules.
Cov tshuaj no tseem muag hauv Octolipen 300 tsiav tshuaj thiab Okolipen 600 ntsiav tshuaj.
Cov lus qhia rau kev siv Oktolipen
Los npaj cov kev lis ntshav tov, koj yuav tsum tau dilute 1 lossis 2 ampoules hauv 50-250 ml ntawm 0.9% sodium chloride tov. Txoj kev daws teeb meem yog muab los ntawm kev poob dej, ncab ib leeg. Nws siv ib zaug ib hnub rau 300-600 mg rau 2-4 lub lis piam. Tom ntej no, koj yuav tsum hloov mus rau kev kho qhov ncauj.
Cov cuab yeej muaj qhov ua qhov muag, uas txhais tau tias cov ampoules yuav tsum tau muab tshem tawm tam sim ntawd ua ntej siv.
Nws yog qhov zoo dua los tiv thaiv cov ntim nrog kev daws los ntawm lub teeb thaum lub sijhawm infusion, piv txwv li, siv ntawv ci lossis lub hnab tiv thaiv lub teeb. Txoj kev daws teeb meem tau muab tso rau hauv qhov chaw tsaus thiab siv rau li 6 teev tom qab kev npaj.
Yog tias tus kws kho mob tau sau tseg ib chav ntawm kev kho mob nrog Oktolipen, ces nws yog ib qho tseem ceeb uas yuav tsum xav txog cov ntsiab lus hauv qab no:
- lipoic acid yuav xav muaj kev hloov pauv hauv lwm cov tshuaj thiab cov khoom noj,
- yog tias cov tshuaj muaj nrog kev tiv thaiv thiab kev kho mob ntshav qab zib, nws yog ib qho tseem ceeb los saib xyuas cov ntshav qabzib hauv cov ntshav siv lub ntsej muag, ua rau muaj kev hloov pauv hauv cov koob tshuaj hypoglycemic,
- cov tshuaj nquag ntawm cov tshuaj muaj ntsis zoo ib yam hauv cov tshuaj B vitamins, tab sis nws tsis yog cov tshuaj vitamin ntxiv. Siv cov khoom lag luam yam tsis tau sab laj nrog kws kho mob tuaj yeem ua teeb meem rau kev noj qab haus huv.
Pharmacological kev txiav txim
Lipoic acid yog tsim nyob rau sab hauv lub cev thaum lub zog oxidative ntawm keto acids. Nws lub peev xwm los tshem tawm cov lus teb ntawm metabolic mus rau insulin tau ua pov thawj. Lipoic acid cuam tshuam ncaj qha rau daim siab, uas yog qhov tseem ceeb rau ntshav qab zib hom 2.
Cov tshuaj tam sim no feem ntau siv hauv kev rog yog tias muaj kev kuaj mob ntawm tus mob ntshav qab zib hom 2 lossis tsis muaj kev kuaj mob.
Lipoic acid ua rau muaj kev cuam tshuam cov txiaj ntsig zoo ntawm lub cev rog. Hauv qab ntawm cov kua qaub no, cov rog rog tau tawg thiab ntau ntau lub zog tso tawm. Rau qhov kev poob phaus, nws tseem yog ib qho tseem ceeb ntxiv los ua kom lub cev ua haujlwm thiab ua raws li kev noj haus kho mob.
Lipoic acid ntes cov carbohydrates, tab sis hloov lawv kom tsis txhob adipose cov ntaub so ntswg, tab sis mus rau cov leeg nqaij, qhov chaw uas lawv tau siv lossis siv rau cov leeg ua haujlwm. Yog li, cov tshuaj siv los txo tus luj tsuas yog ua ke nrog kev noj haus thiab kis las.
Ntau cov kev tshawb fawb qhia tau tias thioctic acid tsis muaj cov nyhuv anabolic ncaj qha.
Oktolipen zoo txo cov lactic acid ntau hauv cov leeg nqaij uas ua rau thaum qoj ib ce. Ib tus neeg tau txais txoj hauv kev los tiv thaiv kev nquag thiab lub caij nyoog ntev, uas cuam tshuam zoo rau kev nyob zoo ntawm ib tug neeg thiab nws lub ntsej muag.
Lipoic acid nce qabzib los ntawm kev mob hlwb. Yog li, txawm tias kev cob qhia me ntsis yuav ua rau nws muaj peev xwm ua kom qhov xwm txheej tom qab haus dej tshuaj yej. Nws yuav tsum tau yug los rau hauv lub siab tias thaum ua cov kev qoj ib ce, cov metabolism hauv lub hlwb nce sai, thiab ntau cov dawb radicals tshwm, uas tau yooj yim neutralized los ntawm lipoic acid.
Cov kev sib txuam thiab cov cim
Oktolipen raug tshuaj rau cov neeg uas tsim cov polyneuropathy ntawm cov ntshav qab zib thiab haus cawv hauv keeb kwm.
Nws kuj tseem qhia txog qhov mob ntsws thiab neuralgia, intoxication nrog ntsev ntawm cov hlau hnyav. Cov neeg uas muaj siab rhiab yuav tsum siv cov tshuaj nrog ceev faj.
Thaum siv cov tshuaj no, cov kev mob tshwm sim hauv qab no yog feem ntau:
- kub siab, xeev siab, ntuav,
- qhov tshwm sim ntawm kev tsis haum tshuaj,
- ntshav qog.
Cov tsos mob ntawm kev noj ntau dua yog:
- ntuav
- xeev siab
- mob taub hau.
Yog hais tias thaum noj thioctic acid nyob rau hauv ib qho nyiaj ntawm 10 txog 40 g, ntau dua kaum ntsiav tshuaj ntawm 600 mg, lossis ntawm ib koob tshuaj ntau dua 50 mg rau ib phaus ntawm lub cev hnyav hauv cov menyuam yaus, tom qab ntawd cov tsos ntawm:
- psychomotor ntxhov siab lossis clouding ntawm nco ntsoov,
- qaug dab peg feem ntau,
- muaj kev cuam tshuam loj heev ntawm cov kua qaub-paus sib npaug nrog cov kab mob lactic acidosis,
- hypoglycemia (mus txog rau qhov uas coma),
- mob leeg pob txha mob necrosis,
- hemolysis
- Cov tsos mob DIC
- hlwb pob txha tsub
- ntau yam hauv nruab nrog cev tsis ua haujlwm.
Yog tias ib qho ntawm cov tshuaj siv thiab ib qho kev noj tshuaj ntau dhau tshwm sim, tsev kho mob tam sim thiab kev siv ntsuas kev ntsuas raws li cov ntsiab lus dav dav thaum muaj teeb meem lom yog qhov tseem ceeb. Koj tuaj yeem:
- ntxias kom ntuav
- yaug lub plab
- coj mus ua hluav ncaig.
Kev kho mob ntawm kev qaug dab peg, lactic acidosis thiab lwm yam cuam tshuam los ntawm lub neej yuav tsum tau ua raws li cov cai ntawm kev saib xyuas hnyav thiab yog cov tsos mob. Yuav tsis nqa txiaj ntsig:
- hemoperfusion,
- hemodialysis
- txoj kev pom thaum thioctic acid tawm los.
Yeeb tshuaj sib cuam tshuam
Cov nyhuv hypoglycemic ntawm cov tshuaj nce ntxiv yog tias nws noj nrog insulin thiab ntsiav tshuaj nrog cov nyhuv zoo sib xws. Qhov no tuaj yeem ua rau kom cov ntshav qab zib muaj ntau ntxiv.
Yog tias siv sib xyaw ua ke yog qhov tsim nyog, tom qab ntawd nws feem ntau yog nrog kev soj ntsuam tas li ntawm cov piam thaj hauv cov ntshav. Thaum pom tau qhov tsis zoo yog qhov nrhiav tau, ntau npaum li cas ntawm cov tshuaj insulin lossis lwm yam tshuaj qog ntshav yuav tsum tau kho sai.
Ethanol thiab metabolites nce qhov feem ntau ntawm cov kev mob tshwm sim. Oktolipen yog tsis sib xws nrog dextrose thiab Ringer daws, nrog rau cov lus sib txuas thiab cov kev daws teeb meem uas cuam tshuam nrog disulfide thiab SH pawg thiab ethanol.
Koj yuav tsum tau saib xyuas 30 feeb ntawm kev noj Okolipen thiab noj cov khoom noj siv mis. Tsis tas li ntawd, kev so zoo li no kuj siv tau rau cov tshuaj nrog:
- hlau
- calcium
Ceev faj kuj tseem yuav tsum sib xyaw Oktolipen nrog cov tshuaj magnesium rau cov ntshav qab zib.
Hauv qhov no, nws yog qhov zoo tshaj plaws los siv Oktolipen thaum sawv ntxov, thiab npaj nrog magnesium, hlau thiab calcium thaum yav tsaus ntuj.
Tsis tas li ntawd, xws li hom tshuaj txo qhov hnyav ntawm kev ua ntawm cisplatin, yog tias cov txhais tau siv ib txhij.
Nqi thiab analogues
Tus nqi ntawm cov tshuaj Okolipen tsis yog qhov siab tshaj plaws. Cov tshuaj ntsiav muaj 300 mg ntawm cov tshuaj tseem ceeb yuav raug nqi 310 rubles.
Octolipen 600 mg ntsiav tshuaj yuav raug nqi li 640 rubles. Hauv cov khw muag tshuaj, koj tseem tuaj yeem pom alpha lipoic acid nws tus kheej. Nws raug nqi tsawg kawg - tsuas yog 80 rubles. Tus nqi ntawm Tiolept yog txog 600 rubles, Tiogamma nqi 200 rubles, Espa-lipon - txog 800 rubles.
Txhais tau hais tias tsis sib txawv hauv kev ua tau zoo thiab tuaj yeem sib hloov ua ke:
- Tiolepta
- Berlition,
- Lipothioxone;
- Alpha lipoic acid,
- Tiogamma
- Thioctacid
- Lipamide
- Neuro lipone
- Es Lias lipon
- Thiolipone.
Qhov tshwj xeeb tshaj plaws, tam sim no yog cov tshuaj Neyrolipon, nws yog qhov kev xaiv zoo rau Oktolipen.
Thioctacid
Thioctic acid yog tam sim no nyob rau hauv kev daws ntawm Thioctacid, thiab thioctate trometamol yog siv nyob rau hauv cov ntsiav tshuaj ntawm lub ntsiav tshuaj.
Thioctacid yog ib hom tshuaj metabolic uas pab txo cov tsos mob ntshav qab zib thiab haus dej cawv nephropathy.
Lub cuab tam muaj:
- antioxidant
- hypoglycemic,
- hepatoprotective cov nyhuv.
Thioctacid normalizes cov kev ua haujlwm hauv lub cev, uas yog qhov tseem ceeb rau cov ntshav qab zib hom 2.
Nws muaj ntau hom tshuaj:
- ntsiav tshuaj
- kev daws rau kev txhaj tshuaj.
Lub ntsiab lus tseem ceeb ntawm cov tshuaj yog cov tshuaj tua kab mob endogenous. Qhov muaj nyob rau hauv lub cev muab:
- yam qab zib raug tshem tawm,
- normalization ntawm trophic neurons,
- kev tiv thaiv ntawm cov hlwb los ntawm kev nqis tes ntawm co toxins,
- txo tus cwj pwm ntawm tus kab mob.
Cov kab mob antioxidant no ib txwm nyob hauv lub cev hauv qhov ntau npaum li cas, thiab txhawb nqa nws ib txwm ua haujlwm.
Cov tshuaj nquag uas muaj nyob hauv cov tshuaj Thioctacid tau nrawm thiab nrawm, thiab qee tawm ntawm lub cev tawm hauv thaj tsam li ib nrab ib teev. Tab sis kev siv cov tshuaj nrog cov zaub mov cuam tshuam rau kev nqus ntawm cov tshuaj tseem ceeb. Bioavailability yog 20%.
Yeej, metabolism yog ua tiav los ntawm oxidation thiab kev sib txuas. Thim ntawm qhov ntau ntawm cov tshuaj yog nqa tawm los ntawm ob lub raum. Thioctacid feem ntau yog kho rau cov mob ntshav qab zib neuropathies.
Xws li cov tshuaj tseem tau sau tseg rau daim siab pathologies. Piv txwv li, ib qho tshuaj kho yog los ntawm:
- mob ntsws
- kab mob siab
- rog lawm,
- fibrosis.
Thioctacid ua rau nws muaj peev xwm tshem tawm cov txiaj ntsig lom uas hloov mus ua hlau.
Tus nqi ntawm cov tshuaj nyob rau hauv daim ntawv ntawm ampoules yog txog 1,500 rubles, ntsiav tshuaj raug nqi los ntawm 1,700 txog 3,200 rubles.
Txiav txim siab saib qhov twg zoo dua: Thioctacid lossis Oktolipen, tus kws kho mob koom nrog yuav pab. Cov txiaj ntsig ntawm lipoic acid rau cov ntshav qab zib yuav tau them rau hauv cov yeeb yaj kiab hauv tsab xov xwm no.
