Ciprofloxacin AKOS yog hais txog cov tshuaj tua kabmob ntawm qhov dav dav thiab hauv ib cheeb tsam ntawm pawg quinolone. Nquag los tawm tsam ntau ntawm cov kab mob pathogenic ntawm cov kab mob pathogen. Cov kws kho mob thiab cov neeg mob nco ntsoov qhov kev ua haujlwm zoo ntawm cov tshuaj.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lub npe tshuaj thoob ntiaj teb nonproprietary ntawm cov tshuaj yog ciprofloxacin.
Ciprofloxacin AKOS yog hais txog cov tshuaj tua kabmob ntawm qhov dav dav thiab hauv ib cheeb tsam ntawm pawg quinolone.
ATX
Raws li ATX, Ciprofloxacin akos muaj tus lej S01AX13.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm dauv, muaj pes tsawg leeg rau kev txhaj tshuaj thiab cov ntsiav tshuaj, mloog zoo.
Ntsiav tshuaj
Txhua ntsiav tshuaj muaj 0.25 lossis 0.5 g ntawm ciprofloxacin hydrochloride 3. Tsis tas li ntawd, cov muaj pes tsawg leeg suav nrog cov qos yaj ywm thiab pob kws hmoov txhuv, talc, talc, silicon dioxide thiab lwm yam kev zam.
Ncos
1 cm³ ntawm tee muaj 3 mg ntawm ciprofloxacin hydrochloride. Cov kev zam uas txhim kho cov nyhuv ntawm cov tshuaj muaj xws li benzalkonium chloride, ethylene diaminetetraacetic acid disodium ntsev, mannitol, sodium triacetate, acetic acid, dej distilled.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov tee.
Tshuaj
Kev daws muaj ciprofloxacin thiab sodium chloride los tswj cov isotonic ntawm tus neeg sawv cev. Lub raj mis muaj 200 cm³ ntawm kev daws.
Pharmacological kev txiav txim
Cov tshuaj muaj qhov qhia tau zoo txog cov nyhuv ntawm cov tshuaj lom neeg txawv. Nws yog ib qho kev tso tawm ntawm fluoroquinolones.
Cov Tshuaj Pharmacokinetics
Cov tshuaj txwv rau qhov rov ua dua ntawm DNA thiab RNA pathogens.
Nws rhuav tshem cov txheej txheem ntawm cov protein ua ke thiab cov kab mob loj hlob ntawm tes. Ua rau muaj kev hloov pauv ntawm cov leeg hlwb. Cov kab mob Gram-cuam tshuam raug cuam tshuam thaum faib kev ua haujlwm thiab dormancy. Cov kab mob Gram-positive cuam tshuam tsuas yog thaum lawv faib.
Rau cov cell ntawm tib neeg lub cev, cov tshuaj muaj tshuaj lom tsawg. Qhov no yog vim tias cov hlwb tsis muaj cov kab mob DNA, rau cov uas ua yeeb tshuaj. Kev siv tshuaj yaj yeeb, txawm hais tias lub sijhawm ntev, tsis muaj yees, qhov kev txhim kho ntawm kev tawm tsam ntawm cov kab mob me me. Qhov no ua rau nws nquag in relation to:
- Escherichia;
- shigella;
- cytobacteria;
- Klebsiella;
- enterobacteria;
- Proteus;
- hafnium;
- morganell;
- vibrios;
- pseudomonads;
- plesiomonas;
- moraxell;
- campylobacter;
- legionella;
- mob chlamydia;
- pseudomonas aeruginosa;
- daim ntawv teev npe;
- Mycobacterium tuberculosis;
- corynebacteria mob hawb pob;
- streptococcus spp;
- streptococcus pyogenes;
- treponema pallidum.
Rau cov cell ntawm tib neeg lub cev, cov tshuaj muaj tshuaj lom tsawg. Qhov no yog vim tias cov hlwb tsis muaj cov kab mob DNA, rau cov uas ua yeeb tshuaj.
Tom qab qhov kawg ntawm kev nqis tes ntawm ciprofloxacin, yuav luag tsis muaj tus kab mob ciaj sia nyob.
Dab tsi yog sau tseg?
Cov tshuaj yog qhia yog tias muaj:
- kis mob los ntawm cov kab mob hauv cov kab mob;
- cov kab mob muaj kev puas tsuaj rau cov hlab ntsws sab saud;
- mob ntsws ua mob hauv daim ntawv mob thiab mob ntev;
- mob ntawm nruab nrab pob ntseg, maxillary sinuses, mob qhov ntswg thiab cov leeg ntshav hauv siab;
- inflammatory pathologies ntawm pharynx thiab larynx;
- mob txhab ntawm ob lub raum thiab mob txeeb zig, suav nrog pyelonephritis;
- prostatitis
- inflammatory pathologies ntawm poj niam lub qhov chaw mos;
- abscesses;
- gonococcal o mob;
- mos chancre;
- mob chlamydial;
- cov kab mob ua rau lub plab zom mov;
- o ntawm cov hlab plab, peritoneum;
- abscesses yog mob plab-plab;
- typhoid fever;
- Salmonella kev hlub
- mob raws plab;
- kev kis mob ntawm cov mob txhab thiab txiav;
- kev mob kis ntawm cov pob txha thiab pob qij txha;
- kev kis kab mob tshwm sim los ntawm kev siv cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kab mob;
- tiv thaiv kev kis mob txhab ntawm kev cuam tshuam thaum phais mob;
- hlwv thiab lwm yam kab mob qhov muag;
- keratitis;
- qhov muag phais (kom tsis txhob o).
Cov tshuaj yog siv rau kev mob ntsws hauv cov mob loj thiab mob ntev.
Cov Yuav Tsum Muaj
Nws yog txwv tsis pub siv nrog hypersensitivity, mob plab, thaum noj tizanidine. Nws tsis raug tso cai los noj tshuaj rau hauv kev kho mob thiab tiv thaiv kev rov huam mob ntawm anthrax. Cov me nyuam lub hnub nyoog yog ib qho txheeb ze sib piv: nws yog txwv tsis pub siv cov tshuaj rau cov menyuam yaus hnub nyoog qis dua 1 xyoos.
Nrog saib xyuas
Kev ceev faj yog qhov yuav tsum tau sau tshuaj noj rau lub siab thiab mob raum, kev ua haujlwm ntawm cov kabmob no.
Cov me nyuam lub hnub nyoog yog ib qho txheeb ze sib piv: nws yog txwv tsis pub siv cov tshuaj rau cov menyuam yaus hnub nyoog qis dua 1 xyoos.
Yuav noj li cas Ciprofloxacin AKOS
Feem ntau, nws raug nquahu kom noj 0.25 g ntawm cov tshuaj 2 mus rau 3 zaug ib hnub. Yog tias cov chav kawm ntawm cov kab mob pathology nyuab, ces xaiv cov ntsiav tshuaj ntawm qhov koob ntawm 0.5 g. Lub tshuaj kho mob thiab noj tshuaj ntau txawv me ntsis rau cov kab mob sib txawv:
- Thaum kis ntawm mob txeeb zig, 0.5 g ntawm Ciprofloxacin siv 2 zaug ib hnub, rau ib lim tiam. Thaum muaj mob hnyav, lub sijhawm kho tau nce mus txog 10 hnub.
- Nrog kab mob gonorrhea, 0.5 tshuaj siv ib zaug. Yog tias tus kab mob gonococcal tau koom ua ke nrog chlamydia thiab mycoplasmas - 0.75 g ntawm ciprofloxacin nrog ib ncua sijhawm ntawm txhua 12 teev.
- Chancroid yuav tsum siv 0,5 g 2 zaug ib hnub rau ob peb hnub.
- Yog tias tus txheej txheem meningococcal tshwm sim hauv lub qhov ntswg, ces 750 mg ntawm cov tshuaj yuav tsum siv ib zaug.
- Yog tias tus neeg mob yog tus neeg muaj tus kab mob Salmonella, noj 4 ntsiav tshuaj ib hnub (0.25 g). Lub chav kawm ntawm kev kho mob nce mus rau 4 lub lis piam, nyob rau qee kis nws tuaj yeem txuas ntxiv. Thaum cov tshuaj ntau ntxiv, koj yuav tsum haus dej haus 0.5 g peb zaug ib hnub.
- Thaum muaj mob ntsws, 3 ntsiav tshuaj siv, 0.25 g 2 zaug ib hnub.
- Nrog rau cov kab mob tsis haum ntawm lub chaw tso zis, quav zis yog qhov zoo dua. Qhov ntau npaum li cas yog 200 mg. Nrog rau cov mob ntawm cov mob kis, cov koob tshuaj tau nce ntxiv rau 400 mg.
Cov tshuaj tuaj yeem muab cov tshuaj drip, tshuaj leeg.
Cov tshuaj tuaj yeem muab cov tshuaj drip, tshuaj leeg. Lub sijhawm tiv thaiv kev poob qis yog 30 feeb (thaum txhaj tshuaj ntawm 0.2 g yog xav tshuaj) thiab 60 feeb (thaum noj ntau ntxiv ntawm 0.4 g yog tshuaj). Npaj cov tshuaj daws tau muab tso ua ke nrog kev sib xyaw isotonic sodium chloride, Lub nplhaib muaj pes tsawg leeg.
Thaum muaj mob ntawm qhov muag, kev kho mob yog nqa tawm los ntawm instillation hauv hnab looj tes sib txuas, 1 lossis 2 tee tom qab 4 teev. Nrog rau tus kab mob hnyav, 2 tee siv rau txhua teev. Nrog rau qhov mob txhab ntawm lub qhov muag, lawv kho kom zoo. Tiv tauj cov qhov muag iav tsis tso cai rau kev tiv thaiv kev mob puas. Txog kev raug mob, lub qhov muag tau sau tseg kom zoo kom tsis txhob puas rau lub pob zeb.
Nrog rau tus mob peritonitis, txoj kev cia siab ntawm cov thawj coj yog siv, i.e. kev daws yog txhaj rau hauv plab plab. Qhov ntau zaus ntawm kev tswj hwm tshuaj yog 0.05 g 4 zaug ib hnub.
Tom qab cov tsos mob ntawm tus kab mob pib ploj, koj yuav tsum haus cov tshuaj rau lwm 3 hnub los tswj kom qhov txiaj ntsig zoo thiab tiv thaiv kev txhim kho mob rov huam tuaj.
Thaum muaj mob ntawm qhov muag, kev kho mob yog nqa tawm los ntawm instillation hauv hnab looj tes sib txuas, 1 lossis 2 tee tom qab 4 teev.
Ua ntej lossis tom qab noj mov
Lub sijhawm ntawm pub nkag - ua ntej lossis tom qab noj mov - tsis muaj teeb meem. Nws yog ib qho tseem ceeb kom tsis txhob haus lawv rau ntawm lub plab khoob, vim hais tias cov nyhuv ntawm cov tshuaj txo.
Nrog ntshav qab zib
Tej zaum qhov kev txhim kho ntawm tus mob ntshav qab zib tsawg nyob rau hauv cov neeg mob ntshav qab zib uas haus tshuaj fluoroquinolones. Ua tib zoo saib xyuas cov ntshav qabzib nyeem yog tsim nyog.
Thaum noj cov tshuaj, cov ntshav qab zib yuav tsum ua tib zoo saib xyuas lawv cov ntshav qabzib nyeem.
Sab sij huam
Kev saib xyuas yuav tsum tau coj mus siv cov tshuaj vim tias nws tuaj yeem ua rau ntau yam phiv. Tus neeg yuav muaj kev ntxhov siab rau kev ua haujlwm ntawm lub plawv thiab ntshav vias. Qhov no tau ua kom pom tseeb hauv daim ntawv ntawm cov ntse thiab cov lus nce hauv cov ntshav siab. Cov kev mob tshwm sim hauv qab no yog ua tau:
- kev tshwm sim ntawm cov ntshav hauv cov zis;
- prolapse ntawm muaju hauv cov zis;
- mob heev thiab sai mycosis;
- kev tso zis;
- cov tsos ntawm albumin hauv nws;
- jade;
- o ntawm cov pob qij txha thiab cov hnab ntim sib koom ua ke;
- candidiasis.
Ib daim paib sab yog qhov pom ntawm ntshav hauv zis.
Kev kho mob txoj hnyuv
Yuav muaj qhov txhab ntxiv ntawm cov hnyuv:
- xeev siab
- zawv plab
- ntuav
- mob hauv plab hauv plab;
- tus ntse txo qis hauv qab los noj mov;
- jaundice los ntawm stagnation ntawm cov kua tsib;
- kab mob siab;
- necrosis ntawm daim siab.
Thaum noj tshuaj, mob hauv plab plab yog ua tau.
Hematopoietic plab hnyuv siab raum
Ib tug neeg yuav mob leukopenia (txo qis hauv cov qe ntshav dawb), granulocytopenia (txo qis ntawm cov granulocytes), thrombocytopenia (txo qis hauv kev ua hauj lwm ntawm cov ntshav plasmaets), ntshav liab. Kev ua txhaum cov ntshav hauv qab no yog ua tau:
- nce hauv prothrombin;
- nce kev ua si ntawm daim siab enzymes;
- nce ntxiv nyob rau theem ntawm creatinine, bilirubin;
- hyperglycemia.
Nruab nrab hauv lub paj hlwb
Thaum lub caij tswj hwm cov ciprofloxacin, kev txhim kho kev mob tshwm sim muaj peev xwm ua tau:
- kiv taub hau heev;
- mob hauv ib nrab ntawm lub ntsej muag zoo li mob taub hau;
- qhia tau tias muaj kev ntxhov siab;
- trembling ntawm cov ntiv tes ntawm lub sab saud;
- kev pw tsaug zog nrog lub ntsej muag tsis pom kev npau suav;
- kev xav txawv ntawm kev hnov mob;
- nce nyiaj ntawm cov hws;
- lub ntsej muag ntse hauv lub siab sab hauv pob txha taub hau;
- tsis meej pem (qee zaum ib tus neeg tsis tuaj yeem paub tias nws nyob qhov twg thiab ua cov ntsiab lus tseem ceeb);
- kev loj hlob ntawm cov hlwb, thaum lub sijhawm kev txhim kho uas ib tug neeg tuaj yeem ua mob rau nws tus kheej thiab lwm tus;
- yastes yastaw
- tsis hnov lus, tsis pom kev, hnov tsw;
- zoo nkaus qhov tinnitus.
Thaum noj Ciprofloxacin, cov kev mob tshwm sim tuaj yeem tsim kho: zoo li pheej muaj tinnitus.
Kev ua xua
Kev tsis haum qhov tshwm sim muaj peev xwm ua tau:
- khaus tawv nqaij;
- urticaria;
- qhov zoo li tus hlwv ntawm daim tawv nqaij;
- kev loj hlob ntawm nodular formations, uas tom qab ntawd hloov mus ua scabs;
- npaws
- cov tsos ntawm petechiae - taw qhia me me hemorrhages thoob plaws lub cev;
- txog siav
- o ntawm lub ntsej muag, tsawg dua - larynx;
- nce rhiab heev rau lub teeb;
- erythema;
- Cov leeg ua kom tawv nqaij (cov tawv nqaij ua haujlwm tawv).
Thaum noj Ciprofloxacin, kev fab tshuaj muaj peev xwm ua tau: khaus ntawm daim tawv nqaij, urticaria.
Cov lus qhia tshwj xeeb
Yog tias tus neeg muaj tus nqi txo qis glomerular, ces ntau npaum li cas ntawm cov tshuaj tau kho. Yog tias nws tsis qis dua 30 ml ib feeb twg rau 1.73 cm³, tom qab ntawd qhov siab tshaj plaws txhua hnub yog 1 g ntawm Ciprofloxacin. Yog tias qhov ntsuas no tsawg dua 30, tab sis siab dua 15, tom qab ntawd qhov kev txhaj tshuaj siab tshaj txhua hnub yog txo rau 500 mg. Yog hais tias tus glomerular pom kev npaum li tsawg dua 15 ml ib feeb ntawm 1.73 cm³, ces tus neeg mob hloov mus rau lim ntshav. Cov tshuaj yog kws kho tsuas yog tom qab kev lim ntshav.
Hauv cov kab mob loj, mob plab, mob staphylococcal, qhov ntau npaum li cas tau nce txog 0.75 g txhua 12 teev.
Cov ntsiav tshuaj yuav tsum nqos tag nrho. Nws yog txwv tsis pub dag nws.
Lub sijhawm kho mob rau cov mob osteomyelitis ntev thiab 2 hlis yog 2 hlis.
Cawv tau zoo
Cov tshuaj yog sib txuam nrog cawv. Rau lub sijhawm kho, txawm tias qhov tsawg tshaj plaws ntawm cov cawv yuav tsum tau tso tseg.
Cov tshuaj yog sib txuam nrog cawv.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Thaum lub sij hawm kho, koj yuav tsum caiv tsis txhob tsav tsheb thiab cov txheej txheem uas yuav tsum tau saib xyuas ntxiv los ntawm ib tug neeg.
Siv thaum cev xeeb tub thiab lactation
Nws yog txwv tsis pub sau ntawv rau noj thaum lub sij hawm xav tias yuav muaj me nyuam thiab pub niam mis. Yog tias nws tsim nyog yuav tau noj tshuaj, ces tus me nyuam mus ib ntus rau kev pub mis.
Nws yog txwv tsis pub sau ntawv rau noj thaum lub sij hawm xav tias yuav muaj me nyuam thiab pub niam mis.
Tshuaj Ciprofloxacin AKOS rau cov menyuam yaus
Cov me nyuam tuaj yeem raug kho rau pyelonephritis, mob tsis tso zis tsis tso zis ntau. Nws yog ib qho tsim nyog yuav tsum pib kho mob tsuas yog tom qab qhov tseeb muab xam ntawm qhov sib piv ntawm kev pheej hmoo thiab txiaj ntsig.
Lub chaw soj ntsuam ntawm kev siv cov tshuaj muaj tsawg.
Siv rau lub sijhawm qub
Rau cov neeg mob laus, cov koob tshuaj tau raug txo los ntawm 30%.
Noj ntau dhau
Raws li qhov pom tseeb ntawm kev noj ntau dhau, qhov mob rov qab ua haujlwm ntawm lub raum plab hlaus rov qab tau qee zaum sau tseg. Kev siv tshuaj ntau dhau ua rau lub raum tsis ua haujlwm. Lwm cov tsos mob:
- Kiv taub hau
- nkees
- cramps
- ua kom pom tseeb;
- tsis xis nyob hauv plab hauv plab;
- daim siab ua haujlwm;
- hais cov lus hematuria.
Yog tias dhau ntawm kev siv tshuaj ntau dhau lawm, koj yuav tsum yaug lub plab, noj tshuaj tiv thaiv kab mob. Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb.
Raws li kev tshaj tawm ntawm kev haus dej dhau, kiv taub hau qee zaum sau tseg.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog kev tswj hwm kom zoo rau ciprofloxacin thiab cov neeg sawv cev barbituric, cov mem tes thiab ntshav siab yuav tsum tau soj ntsuam tas li. Daim cardiogram yuav tsum ua ntu zus.
Thaum noj cov tshuaj tiv thaiv kev puas hlwb, ciprofloxacin yuav tsum ua kom zoo zoo thiab tsuas yog ua qhov kawg yog tias siv tshuaj tua kab mob ntawm cov koob no yuav zam tsis dhau. Ua tsis tiav raws li cov lus pom zoo no ua rau muaj kev puas tsuaj loj rau lub paj hlwb.
Kev tswj hwm ib txhij ntawm lwm cov tshuaj ua rau cov synergism, i.e. txhim kho qhov kev txiav txim ntawm lawv txhua tus. Nws yog siv ua ke nrog ceftazidime, azlocillin, vancomycin, metronidazole, clindamycin. Metoclopramide nrawm kev nqus ntawm cov tshuaj.
Txhim kho lub txiaj ntsig ua kom puas ntawm lub raum cyclosporin.
Kev nqus tau cov khoom noj muaj hlau ua rau txo qis hauv cov tshuaj muaj zog. Kev tswjhwm ntawm cov leeg dua yog muaj kev nyiam dua.
Noj cov tshuaj uas tsis yog tshuaj steroidal thiab ciprofloxacin tsub kom qhov qaug dab peg ntau.
Analogs
Cov lus piv txwv yog:
- Levofloxacin;
- Ciprinol;
- Ciprofloxacin;
- Cyprolet.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj yuav muab faib tawm los ntawm cov tshuaj noj.
Nqe rau ciprofloxacin AKOS
Tus nqi ntawm qhov muag tee yog kwv yees 25 rubles. Tus nqi ntawm cov ntsiav tshuaj yog 10 pcs. 0.5 g txhua - txog 120 rubles.
Cia rau cov neeg mob rau cov tshuaj
Muab cia rau hauv lub ntim thawj hauv qhov chaw tsaus thiab txias.
Hnub tas sij hawm
Nws haum rau 3 xyoos.
Chaw tsim tshuaj paus
Synthesis ntawm AKO, Kurgan.
Kev txheeb xyuas ntawm Ciprofloxacin AKOS
Cov kws kho mob
Svetlana, 50 xyoo, cov kws kho mob tshaj plaws, Moscow: "Kuv pom zoo Ciprofloxacin rau cov neeg mob uas muaj qhov txhab mob ntawm ob lub raum thiab mob tso zis. Tom qab ib lub lim tiam ntawm txoj kev kho, qhov tshwm sim ntawm tus kab mob mus. Cov kev mob tshwm sim tsis tshua muaj."
Irina, hnub nyoog 48 xyoo, kws kho mob, Kirov: "Cov neeg mob ntsws yuav tsum tau kho txhua lub sijhawm ntawm lub xyoo. Qee lub sijhawm nws nyuaj vim tias muaj ntau cov pathogens tiv thaiv tshuaj tua kab mob. Ciprofloxacin zoo rau kev kho mob ntsws thiab lwm yam kev mob ntsws."
Olga, hnub nyoog 40 xyoo, kws kho qhov muag, St. Petersburg: "Ciprofloxacin tee tau txais kev kho mob rau qhov mob tau zoo. Twb tau nyob rau hnub thib peb ntawm kev kho mob, ib qho tseem ceeb txhim kho thiab ruaj khov ntawm tus neeg mob tus mob tau raug pom. Kev sib kis mob sib kis tau raug kho yam tsis muaj kev cuam tshuam thiab kev mob tshwm sim."
Cov neeg mob
Ivan, 25 xyoo, Moscow: "Tom qab dhau daim ntawv sau tseg, qhov mob thiab qhov mob ntawm lub qhov muag tau tshwm sim. Tus kws kho qhov muag tau hais tias yuav tshem tawm Ciprofloxacin tsis pub dhau 5 hnub. Twb tau nyob rau hnub thib peb, kev txhim kho qhov muag thiab qhov mob ploj mus."
Irina, 28 xyoo, Kursk: "Tus me nyuam tau pom tias muaj kab mob ua paug. Nws muaj peev xwm kho tau nrog kev pab ntawm cov menyuam yaus poob ntawm Ciprofloxacin. Cov tsos mob ploj tom qab 4 hnub. Tsis muaj kev phiv."