Gensulin yog kev txhaj tshuaj rau cov ntshav qab zib mellitus. Cov tshuaj yog contraindicated nyob rau hauv cov ntaub ntawv ntawm siab rhiab heev rau lub Cheebtsam, zoo li nrog hypoglycemia.
Gensulin H yog ib qho nruab nrab-lub sijhawm tib neeg lub insulin. Cov tshuaj tau los siv cov qauv tshiab ntawm kev hloov kho engineering. Gensulin H yog siv los tswj cov metabolism hauv qabzib.
Txhais tau tias Gensulin N yog dawb, thaum so nws tso tawm nrog cov nag lossis daus dawb, saum toj no nws yog kua uas tsis muaj xim.
Kws tshuaj thiab muaj pes tsawg leeg
Gensulin H yog tib neeg cov insulin uas yog tsim los siv cov thev naus laus zis siv DNA tshiab. Qhov kev kho no ua raws li kev npaj tshuaj insulin muaj lub sijhawm ua haujlwm nruab nrab.
Cov tshuaj cuam tshuam nrog cov receptors ntawm cytoplasmic sab nraud cov leeg. Ib tug ua yog tsim uas nkoos, as Well as synthesis ntawm cov enzymes tseem ceeb, namely:
- pyruvate kinase,
- xov hexokinase
- glycogen synthetase.
Qhov kev nqis tes ua ntawm insulin npaj yuav ntev nrog tus nqi nqus tau zoo. Qhov ceev no nyob ntawm cov xwm txheej xws li:
- tsuas tshuaj
- thaj tsam thiab txoj kev tswj hwm.
Qhov kev txiav txim ntawm cov khoom yog hloov pauv. Ntxiv mus, qhov no siv rau cov neeg sib txawv, thiab rau cov xeev ntawm tib tus neeg.
Cov tshuaj muaj cov ntawv qhia tshwj xeeb ntawm kev ua. Yog li, qhov cuab yeej pib ua tom qab ib teev thiab ib nrab, nws cov txiaj ntsig siab tshaj plaws tau tiav hauv lub sijhawm 3-10 teev. Lub sijhawm tiv thaiv ntawm cov tshuaj yog 24 teev.
Cov tshuaj muaj pes tsawg leeg muaj 100 IU ntawm tib neeg cov tshuaj insulin rau 1 ml. Cov muaj mob:
- metacresol
- tshuaj glycerol
- tshuaj sulfate,
- zinc oxide
- phenol
- sodium hydrogen phosphate dodecahydrate,
- dej rau kev txhaj tshuaj
- hydrochloric acid rau ib pH ntawm 7.0-7.6.
Lub hauv paus ntsiab lus ntawm kev khiav haujlwm
Gensulin H cuam tshuam nrog cov khoom siv cell membrane. Yog li, ib qho insulin receptor complex tshwm.
Thaum cov khoom ntawm AMP hauv lub siab ua haujlwm nce lossis thaum cov leeg nqaij nkag mus rau hauv cov hlwb, insulin receptor complex pib tsim cov txheej txheem intracellular.
Txo cov ntshav qabzib ntau ntau yog tshwm sim los ntawm:
- kev ua si nyob rau hauv lub hlwb ntau ntxiv
- ntxiv kev nqus ntawm qab zib los ntawm cov ntaub so ntswg,
- protein ua kom sib haum
- ua kom ntawm lipogenesis,
- glycogenesis
- qhov ua kom cov suab thaj txo qis hauv lub siab yog ua los ntawm lub siab.
Cov lus qhia rau kev siv tshuaj
Qhov ntau thiab tsawg ntawm cov tshuaj tau txiav txim los ntawm tus kws kho mob hauv txhua kis ntawm tus kheej. Raws li ntsuas ntawm cov ntshav qab zib cov ntshav concentration, coj mus rau hauv tus account tus yam ntxwv ntawm tus neeg.
Kev txhaj tshuaj rau hauv tus ncej puab yog qhov zoo tshaj plaws, thiab insulin tuaj yeem raug txhaj rau hauv lub pob tw, sab nraub qaum ntsa, thiab deltoid brachial leeg. Qhov ntsuas kub ntawm qhov muab ncua yuav tsum yog chav tsev kub.
Qhov chaw txhaj tshuaj yog thawj zaug ntxuav nrog cawv. Nrog ob tus ntiv tes, quav cov tawv nqaij. Tom ntej no, koj yuav tsum tau ntxig lub koob ntawm lub kaum tsev ntawm txog 45 degrees rau hauv lub hauv paus ntawm quav thiab ua subcutaneous insulin txhaj tshuaj.
Koj tsis tas yuav tshem tawm rab koob ntev li 6 feeb tom qab txhaj tshuaj kom paub tseeb tias cov tshuaj tau muab tshuaj puv nkaus. Yog tias muaj ntshav hauv qhov chaw txhaj, tom qab tshem rab koob, muab qhov chaw tso maj mam nrog koj tus ntiv tes. Txhua lub sijhawm ntawm qhov chaw txhaj tshuaj tau hloov pauv.
Gensulin N yog siv los ua cov tshuaj monotherapy thiab hauv txoj kev kho mob nyuaj nrog siv cov insulins luv luv - Gensulin R.
Hauv daim cartridges muaj lub pob me me ntawm lub khob, uas pab sib tov tov. Koj tsis tas yuav co lub taub hau los yog lub raj mis kom ruaj khov, vim tias qhov no tuaj yeem ua rau tsim kom muaj npuas, uas cuam tshuam nrog txoj kev sau cov nyiaj kom raug.
Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam tas li cov tsos ntawm cov khoom hauv cartridges thiab vials.
Nws yog txwv tsis pub siv cov tshuaj yog tias nws muaj plaub ya ri lossis dawb lo nplaum rau ntawm cov phab ntsa lossis hauv qab ntim.
Kev taw qhia thiab contraindications
Kev siv tshuaj Insulin Gensulin tsis tuaj yeem siv yog tias muaj qhov mob rhiab heev, nrog rau cov ntshav ntog ntshav qab zib.
Cov tshuaj siv tau zoo siv rau ntshav qab zib mellitus hom 1 thiab 2.
Ib qho ntxiv, muaj cov taw qhia hauv qab no:
- theem ntawm kev tsis kam mus rau tshuaj hypoglycemic,
- ib nrab tsis kam rau cov tshuaj hypoglycemic,
- intercurrent pathologies,
- haujlwm
- mob ntshav qab zib vim cev xeeb tub.
Cov kev mob tshwm sim hauv qab no yog paub:
- kev ua xua: ua tsis taus pa ua pa, kub cev, urticaria,
- hypoglycemia: tshee tshee, tsaus muag, mob taub hau, ntshai, insomnia, kev nyuaj siab, tsiv, tsis muaj txav, tsis pom kev thiab hais lus, tsis nco qab, tsis nco qab,
- ntshav qab zib acidosis thiab hyperglycemia,
- pom ib ntus tsis zoo,
- khaus, hyperemia thiab lipodystrophy,
- kev txaus ntshai ntawm coma
- cov tshuaj tiv thaiv kab mob nrog tib neeg cov tshuaj insulin;
- qhov nce ntawm cov tshuaj tiv thaiv titer nrog kev nce hauv glycemia.
Thaum pib ntawm txoj kev kho, tej zaum yuav muaj qhov yuam kev ua kom zoo thiab edema, uas yog xwm ib ntus.
Cov txheej txheem txhaj tshuaj thaum siv cov tshuaj insulin hauv vials
Txhawm rau txhaj tshuaj insulin, cov koob txhaj tshuaj tshwj xeeb yog siv nyob ntawm seb muaj tshuaj npaum li cas. Nws yog qhov zoo dua qub los siv cov koob txhaj tshuaj ntawm tib lub chaw tsim khoom thiab hom. Nws yog ib qho tsim nyog yuav tau kuaj xyuas qhov kev ntsuas hluav taws xob ntawm cov koob txhaj tshuaj, suav txog qhov tshuaj lom ntawm cov tshuaj insulin.
Kev npaj rau qhov kev txhaj tshuaj muaj raws li nram no:
- tshem tawm cov txhuas tiv thaiv cap los ntawm flagon,
- kho lub raj mis lub cork nrog dej cawv, tsis txhob tshem tawm cov roj hmab cork,
- txhaj tshuaj huab cua mus rau hauv cov koob txhaj tshuaj uas haum rau koob tshuaj insulin,
- ntsaws lub koob rau hauv cov roj hmab nres thiab nce cua,
- ntxeev lub raj mis nrog rab koob sab hauv (qhov kawg ntawm rab koob yog nyob rau hauv kev ncua),
- nqa cov khoom kom yog rau hauv cov koob txhaj tshuaj,
- tshem cov pa npuas los ntawm lub koob txhaj tshuaj,
- taug qab qhov tseeb ntawm kev sau cov tshuaj insulin thiab tshem tawm cov koob ntawm lub vial.
Qhov tshuaj yuav tsum tau txhaj nyob rau hauv ib txoj kev. Ua li no, koj xav tau:
- kho cov tawv nqaij nrog haus cawv ntawm qhov chaw txhaj tshuaj,
- mus sau ib daim tawv nqaij hauv koj txhais tes,
- ntxig rau rab koob txhaj tshuaj nrog lwm txhais tes ntawm kaum ntawm 90 degrees. Koj yuav tsum ua kom ntseeg tau tias lub koob tau nkag thiab yog nyob rau hauv qhov tob ntawm daim tawv nqaij,
- txhawm rau tswj cov tshuaj insulin, thawb lub piston tuag tag nrho cov hauv qab, qhia cov tshuaj hauv tsawg dua tsib feeb,
- tshem cov koob tawm ntawm daim tawv nqaij los ntawm kev tuav ib qho dej cawv cawv hauv ze. Nias qhov paj nyob rau qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj,
- Txhawm rau kom tsis txhob ua kom cov nqaij puas tsuaj, koj yuav tsum siv ntau qhov chaw rau txhua qhov kev txhaj tshuaj. Qhov chaw nyob tshiab yuav tsum yog tsawg kawg ntawm ob peb centimeters ntawm ib qho dhau los.
Kev Tsim Tshuaj Cartridge
Cartridges nrog insulin Gensulin N yog xav tau rau kev siv nrog cov phwj syringe, piv txwv li, Gensupen lossis Bioton Pen. Ib tug neeg uas muaj ntshav qab zib yuav tsum ua tib zoo kawm cov lus qhia rau kev siv tus cwj mem zoo thiab ua raws nraim li cov lus pom ntawm cov lus qhia.
Lub thawv ntim khoom siv tsis tso cai sib xyaw nrog lwm cov insulins sab hauv daim cartridge. Lub laub npliag tsis tas yuav rov ntim khoom dua.
Koj yuav tsum sau cov tshuaj uas xav tau ntawm cov tshuaj insulin, uas yog kws kho mob sau tseg. Qhov chaw txhaj tshuaj yuav tsum tau hloov pauv kom ib qho chaw tsis siv ntau tshaj 1 zaug hauv ib hlis.
Koj tuaj yeem sib xyaw Gensulin P txhaj tshuaj nrog kev ncua kev ncua ntawm Gensulin N. Qhov kev txiav txim siab no tsuas yog ua los ntawm tus kws kho mob. Thaum npaj qhov sib xyaw, cov tshuaj insulin nrog lub sijhawm ua haujlwm luv dua, uas yog, Gensulin P, yuav tsum tau xaiv ua ntej mus rau hauv cov phwj.
Cov lus qhia ntawm kev sib xyaw yog tshwm sim raws li tau piav los saum no.
Muaj kev phiv ntau
Cov tsos mob overdose yog qhov tsim ntawm hypoglycemia. Qab zib lossis carbohydrate cov khoom tuaj yeem noj ntawm qhov ncauj rau kev kho mob ntawm theem me. Rau cov neeg mob ntshav qab zib, nws yog qhov tseem ceeb uas koj nqa khoom qab zib, qab zib, dej qab zib, lossis khaub noom nrog koj ua ntu zus.
Kev cuam tshuam ntawm cov metabolism carbohydrate tuaj yeem pom, uas qhia nyob rau hauv qee qhov tsis xis nyob rau ib tus neeg. Hauv qee kis, nws yuav yog:
- kev mob ntshav siab: mob taub hau, blanching ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee ntawm lub qhov kawg, tsis meej kev ntxhov siab, zoo nkaus li kev tshaib nqhis, mob hauv plab ua qhov ncauj,
- vim yog hypoglycemia, coma tuaj yeem tsim,
- cov cim qhia ntawm kev ua kom tsis haum: nyob rau qee qhov, Quincke's edema thiab daim tawv nqaij ua pob, nrog rau qhov mob anaphylactic,
- cov tshuaj tiv thaiv nyob hauv thaj tsam ntawm kev tswj hwm: hyperemia, khaus, o, nrog siv ntev - lipodystrophy mob ntshav qab zib mellitus hauv thaj chaw txhaj tshuaj.
Nrog rau qhov tseem ceeb txo cov piam thaj hauv qab, thiab yog tias ib tus neeg tsis nco qab, nws yog qhov tsim nyog los tswj 40% cov kua nplaum nyob rau hauv cov ntshav. Thaum lub siab nco qab rov qab los, koj yuav tsum noj zaub mov uas muaj cov khoom noj khoom haus carbohydrates.
Qhov no yuav tsum tau ua los tiv thaiv ib txheej txheem ib puag ncig ntawm hypoglycemia.
Cov lus qhia tshwj xeeb
Cov ntshav qab zib cov ntshav muaj peev xwm txo qis thaum tus neeg pauv los ntawm tsiaj insulin mus rau tib neeg insulin. Qhov kev hloov pauv no yuav tsum tau ua kom raug cai thiab tsuas yog ua los ntawm kev saib xyuas kho mob.
Txoj kev ua rau lub ntsej muag hypoglycemia tuaj yeem txo tus neeg lub peev xwm los tsav tsheb, kev pabcuam qee yam txheej txheem. Tus kws kho mob ntshav qab zib tau qhia kom ib txwm muaj li 20 g suab thaj.
Muab cov kua dej ntawm cov tshuaj insulin raug kho thaum:
- kis kab mob
- kev cuam tshuam ntawm cov thyroid caj pas,
- Addison's disease
- Kev Ua Siab Ncaj
- CRF,
- mob ntshav qab zib hauv cov neeg tshaj 65 xyoos.
Kev siv ntshav qab zib yuav pib vim:
- insulin overdose
- tshuaj hloov
- kev ntxhov siab lub cev
- ntuav thiab raws plab
- pathologies uas txo kev xav tau rau cov tshuaj insulin,
- kab mob ntawm daim siab thiab ob lub raum,
- sis cuam tshuam nrog qee yam yeeb tshuaj
- hloov chaw txhaj tshuaj.
Thaum yug menyuam thiab qee lub sijhawm tom qab yug menyuam tas, xav tau cov insulin tsawg dua. Thaum lub sijhawm pub mis, koj yuav tsum tau saib xyuas txhua hnub rau ntau lub hlis.
Cov nyhuv hypoglycemic ntawm cov tshuaj yog nce los ntawm sulfonamides, kuj:
- MAO inhibitors
- carbonic anhydrase inhibitors,
- ACE inhibitors, NSAIDs,
- anabolic tshuaj yuam
- bromocriptine
- tetracyclines
- clofibrate
- ketoconazole,
- mebendazole,
- theophylline
- cyclophosphamide, fenfluramine, Li + kev npaj, pyridoxine, quinidine.
Kev ntsuas thiab tus nqi
Tus nqi ntawm cov tshuaj yog nyob ntawm seb qhov ntau npaum thiab chaw tsim tshuaj paus. Hauv Is Taws Nem, lawv muag cov tshuaj ntawm tus nqi tsawg dua li ntawm cov chaw muag tshuaj.
Tus nqi ntawm Gensulin N txawv ntawm 300 txog 850 rubles.
Cov tshuaj ntawm cov tshuaj yog:
- Biosulin N,
- Cia lub hnab N,
- Cov tshuaj tiv thaiv thaum muaj xwm ceev insulin
- Insuman Bazal GT,
- Kev lees paub NPH,
- Rosinsulin C,
- Tshuaj Insulin Protafan NM,
- Protafan NM Penfill, Daim Ntawv Qhia
- Tshuaj yaug NPH,
- Humodar B 100 Rec.
Cov tshuaj muaj feem ntau kev tshuaj xyuas los ntawm cov neeg uas muaj hom 1 thiab ntshav qab zib hom 2.
Cov lus qhia rau kev siv tshuaj insulin yog teev nyob hauv video hauv kab lus no.
